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HBV DNA含量与慢性乙型肝炎分析

Study on Relationship of HBV DNA Contents and Chronic Hepatitis B
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摘要 目的 探讨慢性乙型肝炎患者血清中病毒血症水平与病情程度的相羞生。 方法  采用FQ -PCR方法检测 12 6例慢性乙型肝炎轻、中、重度患者的血清HBVDNA含量。 结果  慢乙肝轻、中、重度组HBVDNA含量分别是 (4 85± 1 0 )× 10 8- 10 7copy .ml、(3 82± 0 8)× 10 6- 10 5copy .ml、(1 8± 0 5 )× 10 5- 10 4copy .ml。结论 慢乙肝轻、中、重度各组之间的HBVDNA含量差异有显著性 ;中重度组病毒含量与总胆红素水平呈负相关 ,与白 /球比例呈正相关。 Objective To investigate the relationship of the serum virus level in chronic B hepatitis cases and their conditions.Methods The serum B hepatitis virus DNA level was detected by FQ-PCR in 126 chronic B hepatitis cases.Results The serum B hepatitis virus level was (4.85±1 0)×10 8-10 7 copy.ml,(3.82±0.8)×10 6-10 5 copy.ml and (1.8±0.5)×10 5-10 4 copy.ml in the light,middle and severe group of chronic B hepatitis respectively.Conclusion There was significant difference among the serum B hepatitis virus DNA level of the light,middle and severe group of the chronic B hepatitis patients.The serum B hepatitis virus DNA level in the middle and severe group of chronic B hepatitis cases inversely correlated with the serum TB level,but positively related to the ratio of A/G.
作者 葛如玲
出处 《医药论坛杂志》 2003年第21期23-23,25,共2页 Journal of Medical Forum
关键词 HBV DNA 含量 慢性乙型肝炎 聚合酶链反应 hepatitis virus B DNA polymerase chain reaction
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