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透明质酸及其在肿瘤中的生物学行为特征 被引量：3

Hyaluronan and its biological behaviors characterization in tumor
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摘要 实体肿瘤细胞可以分泌和降解透明质酸 (HA) ,改变HA的代谢速度 ,使降解产物聚集。HA及其降解产物可调节细胞膜及细胞内HA配体产生及数量 ,其结合物介导多种肿瘤细胞生物学效应 。
作者 曲军英 李桑 马炎辉
机构地区 福建医科大学附属第一医院妇产科
出处 《国外医学（肿瘤学分册）》 CAS 2003年第5期339-342,共4页 Foreign Medical Sciences (Cancer Section)
关键词 透明质酸 肿瘤 生物学行 粘附分子
分类号 R730.2 [医药卫生—肿瘤]
  • 相关文献

参考文献19

  • 1Lipponen P, AMtoma,a S, Tamnfi R, et al . High stromal hyaluronan level is as~ziated with poor differentiation and metastasis in prostate cancer[J]. Eur J Cancer, 2001, 37(7): 849-856.
  • 2Anttila MA, Tammi RH, Tammi MI, et al. High levels of stromal hyaluronan predict poor disease outcome in epithelial ovarian cancer [J]. Cancer Res, 2000, 60(1): 150-155.
  • 3Majumdar M, Meenakshi J, Goswami SK, et al. Hyaluronan bindhag protein 1 (HABP1)/C1QBP/p32 is an endogenous substrate for MAP kinase and is translocated to the nucleus upon rnitogenic stimulation[J]. Biochem Biophys Res Commun, 2002, 291(4): 829-837.
  • 4Assmann V, Gillett CE, Poulsom R, et al. The pattern of expression of the microtubule-binding protein RHAMM/IHABP in mammary carcinoma suggests a role in the invasive behaviour of tumour cells [J]. J Pathol, 2001, 195(2): 191-196.
  • 5Rein DT, Roehrig K, Schondorf T, et al. Expression of the hyaluronan receptor RHAMM in endometrial carcinomas suggests a role in tumour progression and metastasis [ J ]. J Cancer Res Clin Oncol, 2003, 129(3): 161-164.
  • 6Banerji S, Ni J, Wang SX, et al. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan[J]. J Cell Biol, 1999, 144(4): 789-801.
  • 7Jackson DG. The lymphatics revisited, new perspectives from the hyaluronan receptor LYVE-1[J]. Trends Cardiovasc Med, 2003, 13(1): 1-7.
  • 8Slevin M, Kurnar S, Gaffney J. Angioganic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial ceil mirogenic and wound healing responses [ J ]. J Biol Chem, 2002, 277(43): 41046-41059.
  • 9Kobayashi H, Suzuki M, Kanayama N, et al. CD44 stimulation by fragmented hyaluronic acid induces upregulation of urokinase-type plasminogen activator and its receptor and subsequently facilitates invasion of human chondrosarcoma cells[J]. Int J Cancer, 2002, 102(4) : 379-389.
  • 10Liu N, Crao F, Hart Z, et al. Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells[J ]. Cancer Res, 2001, 61(13): 5207-5214.

同被引文献22

  • 1蔡建良,叶章群,杨为民,陈志强,陈春莲.透明质酸在膀胱移行细胞癌、乳头状瘤组织中的表达及其意义[J].中华实验外科杂志,2004,21(10):1226-1228. 被引量：8
  • 2Toole BP. Hyaluronan promotes the malignant phenotype [J].Glycobiology, 2002, 12 (3) : 37 R - 42R.
  • 3Naor D, Nedvetzki S, Golan I, et al. CD44 in cancer [J]. Crit Rcv Clin Lab Sci,2002, 39 (6):527- 579.
  • 4Thylen A, Hjerpe A, Msrtensson G. Hyaluronan content in pleural fluid as a prognostic factor in patients with malignant pleural mesothelioma [J]. Cancer,2001,92(5): 1224- 1230.
  • 5Lipponen P, Aalromaa S, Tammi R, et al. High stromal hyaluronan level with poor differentiation and metastasis in prostate cancer [Jl. Eur J Cancer,2001, 37(7): 849 -856.
  • 6Ropponen K, Tammi M, Parkkinen J, et al, Tumor cell-associated hyalnronan as unfavorable prognostic factor in colorectal cancer [J]. Cancer Res, 1998,58(2): 342 - 347.
  • 7Anttila MA, Tammi RH, Tammi MI, et al. High Levels of stromal hyaluronan predict poor disease outcome in epithelial ovarian cancer [J]. Cancer Res,2000, 1 (60): 150 - 155.
  • 8Herrera-Gayol A, Jothy S. Effects of hyaluronan on the invasive properties of human breast cancer cells in vitro [J]. Int J Exp Pathol, 2001,82 (3) : 193 - 200.
  • 9Liu N, Gao F, Han Z, et al. Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells[J]. Cancer Res, 2001,61(13):5207-5214.
  • 10Hoffman R, Benz EJ, Shattil SJ, et al. Hematology-Basic Principles and Practice. Science Press, Churchili Livingstone, 2000,139-143.

引证文献3

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国外医学（肿瘤学分册）
2003年 第5期

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