摘要
目的 :研究大黄附子汤中各组分不同配伍对附子中乌头碱含量的影响。方法 :以大黄附子汤为基础 ,配伍成不同的组方 ,采用不同的提取工艺 ,应用紫外分光光度法测定乌头碱的含量。结果 :各组方单煎混合提取液中乌头碱的含量比附子单煎下降20 %左右 ,各组方合煎提取液中乌头碱的含量比附子单煎下降45 %左右 ;细辛与附子配伍对乌头碱的含量无影响。结论
OBJECTIVE:To study the influence of different herb composition on content of aconitine in Rhubarb and Aconite Decoction.METHODS:On the basis of Rhubarb and Aconite Decoction,different prescriptions were made up and different deˉcocting technics were adopted,then the content of aconitine was determined with UV-spectrophotometry.RESULTS:The content of aconitine in mixture of decoctions of single herb decreased about20%and the content of aconitine in the decoction of combined herbs decreased about45%compared with that in decoction of single Aconite.Combination of Asarum with Aconite showed no influence on the content of aconitine.CONCLUSION:Rhubarb can control the toxicity of Aconite in Rhubarb and Aconite Decoction.
出处
《中国药房》
CAS
CSCD
2003年第10期634-635,共2页
China Pharmacy
关键词
大黄附子汤
乌头碱
紫外分光光度法
Rhubarb and Aconite Decoction
aconitine
UV-spectrophotometry
