摘要
目的 :探讨鼻内镜术中光和热对鼻黏膜的损伤。方法 :应用透射电镜技术 ,观察正常和光照不同时间后的兔鼻中隔黏膜及其改变。结果 :发现光照后纤毛分布不均 ,有粘连及脱落 ;随照射时间的延长 ,出现上皮细胞间距增大 ,纤毛分布稀疏、粗细不等 ,胞内线粒体肿胀、嵴消失 ,基质空泡化 ,上皮细胞核曲边 ,染色质呈块状分布、边集 ,细胞核接近细胞表面 ,且可见杯状细胞脱落。结论 :鼻内镜术中光和热对鼻黏膜及黏液纤毛有损伤作用 ,鼻内镜手术应尽量缩短手术时间 。
Objective:To investigate the injury of nasal mucosa in transnasal endoscopic sinus surgery by light and heat.Method:The techniques of transmission electron microscope and scanning electron microscope were applied in order to observe the changes between normal and irradiation nasal septum mucosa of rabbits.Result:It showed that after irradiation, the cilia became maldistributed, adhensive and exfoliative. With the elongation of irradiation, the spacing of the epithelium cells increased, the distribution of the cilia was sparse and the degree of their thickness was different, the mitochondria were highly bloated,accompanied with disappearance of the cristae and vacuolation of matrix,the nucleus of epithelium cells was edge-located, the distribution of the chromatin was mass, concentrated by the fringe, the nucleus was close to the cell surface and the exfoliation of goblet cells was visible.Conclusion:The light and heat in transnasal endoscopic sinus surgery can injure the nasal mucosa.
出处
《临床耳鼻咽喉科杂志》
CAS
CSCD
北大核心
2003年第11期670-671,共2页
Journal of Clinical Otorhinolaryngology
关键词
内镜手术
鼻黏膜
损伤
Endoscopic surgery
Nasal mucosa
Injury
