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慢性肾功能衰竭病人周围神经电生理变化的分析 被引量:1

Analysis of peripheral neural electrophysiological p arameters in patients with chronic renal failure
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摘要 目的 研究慢性肾功能衰竭病人周围神经传导的电生理变化各项指标及其临床意义。方法 选择慢性肾功衰竭病人 35例及同期健康对照者 16例 ,并按肌酐水平将慢性肾功能衰竭病人分成 3组 ,通过检测正中神经感觉及运动神经传导的电生理指标 ,分别进行比较。结果 慢性肾功能衰竭组与对照组相比 ,潜伏期及神经传导速度有显著性差异 (P <0 .0 5 ) ,慢性肾功能衰竭各组间运动及感觉神经传导速度有显著性差异 (P <0 .0 5 )。结论 ①慢性肾功能衰竭病人中周围神经病变的电生理变化主要为运动及感觉神经的潜伏期延长 ,神经传导速度减慢 ;②慢性肾功能衰竭的严重程度与周围神经病变的严重程度相关 ,可通过神经传导速度的减慢程度来评估肾功能衰竭的程度。 Objective To study the electrophysiological parameters of periphe ral nerves in patients with chronic renal failure and the clinical significance .. Methods Selected 35 patients with chronic renal failure and 16 nor mal volunteers. The patients with chronic renal failure were divid ed into 3 groups by the crea tinine of serum. Electrophysiological parameters including motor and sensory ner ves were measured for the median nerve and compared with each other. Results Chronic renal failure compared with normal volunteers,the l atency and nerve conduction velocity had significant differences (P<0.05);the nerve conduction velocity had significant differences in the chronic r enal failure (P<0.05). Conclusion ①The electrophysiological parameters of peripheral nerv es are prolongation of latency and low nerve conduction velocity. ②There is cor r elation between the degree of deterioration in chronic renal failure and polyneu ropathy. The degree of deterioration in chronic renal failure can be evaluated b y the low nerve conduction velocity.
出处 《哈尔滨医科大学学报》 CAS 2003年第5期429-430,436,共3页 Journal of Harbin Medical University
关键词 慢性肾功能衰竭 周围神经病变 电生理 神经传导 潜伏期 chronic renal failure polyneuropathy nerve conduction electrophysiological change
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