摘要
目的 测定铜绿假单胞菌对 13种抗菌药物的耐药性 ,为临床合理应用抗生素提供依据。 方法 采用VITEK -3 2型全自动微生物分析仪测定 10 0株铜绿假单胞菌的药敏和超广谱 β -内酰胺酶。 结果 铜绿假单胞菌对氨苄西林、阿莫西林 棒酸、替卡西林 棒酸、头孢他定和头孢噻肟的耐药率超过 90 % ,妥布霉素、庆大霉素、丁胺卡那霉素、环丙沙星、左旋氧氟沙星、亚胺培南为 71%～ 82 % ,未发现对羧苄西林和诺氟沙星的耐药菌株。铜绿假单胞菌产生其超广谱 β -内酰胺酶为 2 6%。结论 羧苄西林和诺氟沙星对铜绿假单胞菌的耐药率最低 。
Objective To determine antimicrobial resistance of pseudomonas aeruginosa to thirteen antbiotics. Methods 100 strains bacterial susceptibility of psendomonas aeruginosa and extended spectrum β-Lactamaes (ESBLs)were tested by VITEK-32 system.Results Resistant percentage to Ampicillin,Amoxicillin/clavulanic acid,Ticarcillin/clavulanic acid, Ceftazidime and cefotoxime was higher than 90%,Tobramycin, Gentamycin, Amikacin,Ciprofloxacin,Levofloxacin,Imipenem was 71%～82%,But no showed resistance to Carbenicillin and Nonfloxacin. ESBLs of pseudomonas aeruginosa was 26%. Conclusion Carbenicillin and norfloxacin were the lowest resistant rate against pseudomonas aeruginosa,they should be antibiotics of the first choice for treatment of clinical infection with pseudomonas aeraginosa.
出处
《中国热带医学》
CAS
2003年第6期774-775,共2页
China Tropical Medicine
