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不同基质配比对青辛速释贴质量的影响 被引量:28

Effect of different proportion of matrix on quality of Qingxin Sushi Tie
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摘要 目的 选择以明胶、西黄蓍胶、甘油、聚丙烯酸钠和青黛制备青辛速释贴的最佳基质配比。方法 应用正交试验法 ,分别以粘度、软硬度、清凉感和刺痛感为衡量指标 ,综合评定不同基质配比下青辛速释贴的质量。结果 青辛速释贴的最佳基质配比为明胶∶西黄蓍胶∶甘油∶聚丙烯酸钠∶青黛 (8.0∶ 3 .5∶ 2 0∶ 1.3∶ 3 .0 )。 Object To select the optimum proportion of matrix f or the preparation process of Qingxin Sushi Tie (QST) by gelatia, gum tragacanth , glycerol, sodium acylate and Qingdai. Methods The process was studied by orthogonal test with visco sity, soft and hard measurement algefacient sentation, twinge sentation as detec tive marker. The quality of QST was comprehensively compared by the different pr oportion of matrix. Results The optimum proportion of matrix in QST was gelatia-gum tyagacanth-glycerol-sodium acylate-Qindai (8 0∶3 5∶ 20∶1 3∶3 0). Conclusion According to the optimum proportio n of matrix in QST, the QST with better quality can be prepared.
出处 《中草药》 CAS CSCD 北大核心 2003年第9期797-799,共3页 Chinese Traditional and Herbal Drugs
基金 广东省中医药管理局立项课题 ( 0 996 2 8)
关键词 青辛速释贴 基质 正交试验 Qingxin Sushi Tie (QST) matrix orthogonal test
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参考文献2

  • 1Cai G Q,Zhou J,Xu Y.Study on removing method of harmful safrole in Herba Asari volatile oil [J].Chin Tradit Pat Med(中成药),1997,19(7);37.
  • 2Du X M,Guo Q,He Y.Comparison of pharmacodynamics between traditional preparation of Chinese patent medicines and preparation made in ultramicro particles[J].Chin Tradit Pat Med(中成药),2000,22(4):307—309.

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