摘要
如何确定实体瘤患者是否具有转移倾向一直是临床上普遍关心的问题 ,而骨髓在肿瘤转移的过程中发挥重要作用 ,无论是易发生还是罕见骨转移的肿瘤患者骨髓中癌细胞的检出率均较高 ,该理论为骨髓微转移检查提供了依据 ,且多年来的研究表明骨髓微转移检查在预后、分期、指导治疗及疗效监测方面越来越显示出其临床应用价值 ,因此作者就骨髓微转移的概念、检查方法及临床应用价值作一综述 。
It is always interesting that how to judge the the disseminative possibility of patients with solid tumors.Bone marrow play an important role in the process of tumor metastasis.The presence of individual tumor cells in bone marrow can be detected by immunologic or molecular methods and is being regarded increasingly as a clinically relevant prognostic factor.The early detection of micrometastases could identify the patients at high risk of metastasis who are most(and least) likely to benefit from adjuvant therapy.This review examines the methods used,results obtained and the clinical significance of studies in this field.
出处
《东南大学学报（医学版）》
CAS
2003年第5期358-362,共5页
Journal of Southeast University(Medical Science Edition)
