摘要
目的 :研究嗜麦芽窄食单胞菌分布特点、分析其对常用抗菌药物的耐药性 ,指导临床合理用药。方法 :用MicroScanWalkAway 4 0全自动微生物鉴定和药敏系统对从我院临床标本中分离的 5 91株嗜麦芽窄食单胞菌进行鉴定和药敏试验。结果 :5 91株嗜麦芽窄食单胞菌的标本来源以痰标本为主 ,占 92 .1 % ,其次为伤口分泌物和胆汁。其临床科室中分布前 6位依次是重症监护病房 (ICU)、呼吸内科、胸心外科、老年科、血液内科和普外科。 5 91株嗜麦芽窄食单胞菌对复方磺胺甲唑和环丙沙星的耐药率较低 ,分别为 2 4 .4 %和 37.1 % ;其对氨苄西林 舒巴坦、头孢噻吩、头孢唑林、头孢呋肟、头孢曲松、头孢噻肟、氨曲南、头孢吡肟、头孢西丁、亚胺培南、庆大霉素、妥布霉素和阿米卡星高度耐药。结论 :临床嗜麦芽窄食单胞菌分离以痰标本为主 ,其临床分布主要为ICU和呼吸内科 ,对嗜麦芽窄单胞菌引起感染的经验治疗 。
Objective: To investigate the distribution patterns and resistance of S. maltophilia in West China Hospital. Methods: MicroScan WalkAway 40 was used for the identification of 591 S. maltophilia clinical isolates and test the susceptibility. Results: Most of 591 strains were isolated from sputum(92.1%), the others were from wound secretion and bile. 591 strains were isolated from ICU, departments of respiratory diseases, cardiothoracic surgery, geriatrics, hematology and general surgery. Results of susceptibility test showed that the resistance rates of trimethoprim sulfamethoxazole were 24.4% and ciprofloxacin 37.1%. S. maltophilia was highly resistant to ampicillin sulbactam, cephalothin, cefuroxime, ceftriaxone, cefotaxime, aztreonam, cefepime, cefoxitin, imipenem, gentamicin, tobramycin and amikacin. Conclusions: Most strains of S. maltophilia are isolated from sputum of patients in ICU and department of respiratory diseases. Trimethoprim sulfamethoxazole and ciprofloxacin are relatively active against S. maltophilia.
出处
《中国抗感染化疗杂志》
CAS
2003年第4期217-219,共3页
Chinese Journal of Infection and Chemotherapy
关键词
嗜麦芽窄食单胞菌
药敏分析
全自动微生物鉴定和药敏系统
S. maltophilia
Susceptibility analysis
Automated microbial identified and susceptibility system
