摘要
嗜麦芽窄食单胞菌(Stenotrophomonasmaltophilia,S.m)是全球关注的8种多重耐药菌株之一,临床治疗非常棘手。重症监护病房(ICU)是嗜麦芽窄食单胞菌感染的多发科室,检出率为13.45%(62株/461株),耐药特征:亚胺培南、头孢唑林、头孢曲松、氨苄西林、米诺环素耐药率最高(耐药率100%),氨曲南、庆大霉素、卡那霉素、美洛培南、头孢噻肟、哌拉西林高度耐药(?86.5%),左氧氟沙星、加替沙星和头孢吡肟耐药性较高(?50%)。结论:医院应重视该菌的监测,合理使用抗菌药,感染患者应严格消毒隔离管理。头孢哌酮/舒巴坦对嗜麦芽窄食单胞菌有较高的抗菌活性(敏感率90.6%),可作为治疗的首选抗菌药。
Stenotrophomonas maltophilia is among eight strain of broad resistance to antibacterial. It has been pay attention to global students, and is very difficulty in clinic treatment. Infection of Stenotrophomonas maltophilia is more familiar in ICU. Its test rate is 13.45% （62/461） in the study. The resistance character： IPM, CZO, CRO, AMP and MNO is highest （ resistive rate 100% ） . ATM, GEN , KAN , MEM , CTX and PIP is much high （ ≥ 86. 5% ）, LVX , GAT and FEP is high （ =50% ）. Conclusion： Stenotrophomonas maltophilia should be monitored in the hospital. Used of antibacterial must be rational. Severe disinfection and isolation should been put in practice to the infected patients. CSL is very active antibacterial （ active rate 90. 6% ） against Stenotrophomonas maltophilia in the study, and ought be selected headmost in treated its infection.
出处
《微生物学通报》
CAS
CSCD
北大核心
2006年第5期183-187,共5页
Microbiology China
