摘要
收集7～31周人胚胎80例,用组织化学方法、免疫组织化学方法及透射电镜观察甲状腺的组织发生。7～8.5周腺体为上皮性细胞索,细胞质内糖原丰富。12～12.5周出现滤泡和滤泡中心的胶质,细胞质内糖原减少。12.5周胎开始观察到C细胞,分布于侧叶的后上部位,单个分散存在,或数个细胞聚集成群。C细胞多居滤泡上皮细胞间,或滤泡上皮细胞与基膜间,滤泡间较少。C细胞在胎期的形态可分3型:1.圆形或卵圆形;2.锥形或多边形;3.具有一胞质突的大细胞。电镜下C细胞分泌颗粒少。半薄切片镀银后,C细胞有嗜银性。
Thyroid glands from 80 human fetuses, 7～31 weeks in gestational age were obtained to study the morphological development of thyroid glands by histochemical, immunohistochemical and TEM techniques. During 7～8.5 weeks the glands composed mostly of epithelial cell cords and abundant glycogen were seen in the cytoplasm of the cells. Some follicles and small accumulations of colloid in the center of the follicles appeared at 12～12.5 weeks and less glycogen was found in the cells.
C cells were distributed mainly in the posterior region of the upper pole of both lobes, they usaually occurred singly or in small groups. During intrauterine life, C cells occupied three positions. They are found between follicular cells, between follicular cell and basement membrane and between follicles. But they are situated predominantly in the follicular wall. Three morphological variants were found in the human fetal C cells: (1) spherical or oval cells, (2) polygonal or pyramidal cells (3) cells with a cytoplasmic process. Developing C cells seem to have few secretory granules by TEM and argyrophilic reaction in semithin sections.
出处
《解剖学报》
CAS
CSCD
北大核心
1992年第2期217-220,共4页
Acta Anatomica Sinica
基金
国家自然科学基金
关键词
人胚胎
组织发生
甲状腺
C细胞
Human fetus
Histogenesis
Immunohistochemistry
Parafollicular cell (C cell)
Thyroid
