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DNA聚合酶β与肿瘤发生的关系 被引量：2

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作者 韩丽萍 董子明 史惠蓉
机构地区 [ [
出处 《实用癌症杂志》 2003年第3期315-317,共3页 The Practical Journal of Cancer
基金 国家自然科学基金资助项目 (编号 :39870 2 87)
关键词 肿瘤发生 DNA聚合酶Β DNA修复损伤 跨损伤合成 结直肠癌 淋巴瘤 胃癌 前列腺癌
分类号 R730.231 [医药卫生—肿瘤]
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参考文献22

  • 1董子明,赵国强,赵勤,杨洪艳,薛乐勋,谭晓辉,郑乃刚.人食管癌组织中DNA聚合酶β基因突变的研究[J].中华医学杂志,2002,82(13):899-902. 被引量：42
  • 2Chyan YJ, Ackerman S, Shepherd NS, et al. The human DNA polymerase βgene structure [J]. Evidence of alternative splicing in gene expression. Nucleic Acids Res,1994,22(14):2719.
  • 3Bennett RA,Wilson DM,Wong D,et al. Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway[J]. Proc Natl Acad Sci USA, 1997,94(14):7166.
  • 4Dianov GL, Prasad R, Wilson SH, et al. Role of DNA polymerase β in the excision step of long patch mammalian base excision repair[J] .J BiolChem, 1999,274(20) : 13741.
  • 5Wood RD, Shiviji MK. Which DNA polymerases are used for DNA-repair in eukaryotes? [J]. Carcinogenesis, 1997, 18(4) :605.
  • 6Pero RW,Ritehie M,Winawer SJ ,et al. Unscheduled DNA synthesis in mononuclear leukocytes from patients with colorectalpolyps[J]. Cancer Res, 1985,45:3388.
  • 7Wang L, Patel U, Ghosh L, et al. DNA polymerase βmutation in human colorectal cancer [J]. Cancer Res, 1992,52:4824.
  • 8Bhattacharyya N, Banerjee S. A variant of DNA polymerase β acts as a dominant negative mutant[J]. Proc Natl Acad Sci USA,1997,94(19) : 10324.
  • 9Kubota Y, Murakami-Murofushi K ,Shimada Y,et al. Reduced fidelity of DNA synthesis in cell extracts from chemically induced primary thymic lymphomas of mice [J]. Cancer Res, 1995, 55(17):3777.
  • 10Iwanaga A,Ouchida M, Miyazaki K,et al. Functional mutation of DNA polymerase beta found in human gastric cancer-inability of the base excision repair in vitro[J]. Mutat Res, 1999, 435(2):121.

二级参考文献10

  • 1Wang L,Li W,Wang X,et al.Genetic alterations on chromosomes 3 and 9 of esophageal cancer tissues from China[].Oncegene.1996
  • 2Weber CA,Salazar EP,Stewart SA,et al.ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3[].EMBO Journal.1990
  • 3Eydmann ME,Knowles MA.Mutation analysis of 8p genes POLB and PPP2CB in bladder cancer[].Cancer Genetics and Cytogenetics.1997
  • 4Widen SG,Kedar P,Wilson SH.Human beta-polymerase gene.Structure of the 5’-flanking region and active promoter[].Journal of Biological Chemistry.1988
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  • 6Dobashi Y,Shuin T,Tsuruga H,et al.DNA polymerase beta gene mutation in human prostate cancer[].Cancer Research.1994
  • 7Wang L,Zhu D,Zhang C,et al.Mutations of O6-methylguanine-DNA methyltransferase gene in esophageal cancer tissues from Northern China[].International Journal of Cancer.1997
  • 8Miller MR,Chinault DN.The roles of DNA polymerases alpha, beta,and gamma in DNA repair synthesis induced in hamster and human cells by different DNA damaging agents[].Journal of Biological Chemistry.1982
  • 9SenGupta DN,Zmudzka BZ,Kumar P,et al.Sequence of human DNA polymerase beta mRNA obtained through cDNA cloning[].Biochemical and Biophysical Research Communications.1986
  • 10Cleaver JE.Structure of repaired sites in human DNA synthesized in the presence of inhibitors of DNA polymerases alpha and beta in human fibroblasts[].Biochimica et Biophysica Acta.1983

共引文献41

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实用癌症杂志
2003年 第3期

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