摘要
目的 观察经支气管镜介导微波热凝固疗法加全身化疗治疗气道阻塞晚期肺癌患者的疗效。方法 将 44例晚期肺癌患者随机分为观察组 ( 2 2例 )与对照组 ( 2 2例 ) ,观察组采用电子支气管镜介导下 ,用微波治疗仪配合单极同轴天线伸至瘤体行凝固冶疗并卡铂 ,依托泊甙 (CE方案 )常规化疗。对照组单用CE方案化疗。结果 观察组 2 2例中完全缓解 8例 ,部分缓解 12例 ,无变化 2例 ,有效率 91%明显高于对照组有效率 ( 5 5 % ) P <0 0 5。结论 经电子气管镜介导微波热凝固疗法能较快使肿瘤缩小或消失 ,解除患者气道阻塞 ,全身化疗可明显缓解因肺癌原发灶 ,转移灶所引起的症状 。
Objectives To observe the effectiveness of bronchoscope guided microwave heating coagutation therapy(HCT)combined with systematic chemotherapy in treating advanced lung cancer.Methods 44 patien with advanced bronchogenic carcinoma were divided into the test group(22 patients)and the control group(22 patients)randomly.Test group received HCT through needle mono pole microwave antenna guided by bronchoscope combined with the routine Carboplatin and etoposide (CE)regimen.While the control group was treated only by chemotherapy with the routine CE regimen.Results in the 22 patients,8 were completely cured and 12 showed partial recovery,the other 2 without any change.The 91% effective rate was significantly higher than 55% of the control group (P<0 05).Conclusions Microwave HCT guided by bronchoscope can remarkably reduce the size of tumour,and the relieve symptom of dyspnea.The systematic chemotherapy alleviates the obstruction caused by tracheal or bronchial neoplasms.The combined therapy leads to much better therapeutic effect and symptomatic relief than those by the routine CE regimen.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2003年第5期298-299,共2页
Chinese Journal of Practical Internal Medicine
