摘要
目的 :评价微生态制剂治疗婴幼儿腹泻病的临床疗效 ,为合理应用微生态制剂治疗婴幼儿腹泻提供指导。方法 :对婴幼儿腹泻病患儿住院治疗期间应用微生态制剂治疗情况进行回顾性调查 ,运用Kaplan- Meier( K- M)法对不同微生态制剂治疗婴幼儿腹泻病的临床疗效进行时间 -效应分析。结果 :4 70例婴幼儿腹泻病患儿住院治疗期间 ,有 4 5 3例患儿有应用微生态制剂治疗 ,占 96 .4 % ;其中 ,选用培菲康、整肠生的病例最多 ,分别有 2 37例和 198例 ;多种微生态制剂联合应用有 83例 ( 18.32 % )。K- M法分析显示 :培菲康治疗婴幼儿急性腹泻病的疗效优于整肠生组及多种微生态制剂联合应用组 ;无论是急性腹泻病 ,还是迁延性、慢性腹泻病 ,多种微生态制剂联合应用治疗的临床治愈时间均不优于单用微生态制剂组。结论 :适当应用微生态制剂有助于婴幼儿腹泻的恢复 ,但盲目采用多种微生态制剂联合治疗并不能提高临床疗效 。
Objective:To investigate the current situation of microecological preparations therapy in children with diarrhea and to assess the effect of several microecological preparations on the treatment of diarrhea among young children less than 3 years of age Methods:The authors analyzed the clinical data of inpatients with diarrhea in the department of pediatrics, the first affiliated hospital of Fujian Medical University during 1997～2001 and used time effect analysis to evaluate the effect of different microecological preparations on children's diarrhea by Kaplan Meier assay Results:Among 470 young children with diarrhea,453(96 4%) were treated with microecological preparations There were 237 with Bifid Triple Viable Capsule,198 with Bacillus Licheniformis Capsule and 83 with combinations of different microecological preparations By Kaplan Meier assay, a course of Bifid Triple Viable Capsule was the most effective treatment for acute diarrhea Whatever acute,chronic or persistent diarrhea,the course of combinations of different microecological preparations had not the advantage of being shorter comparing to the other two Conclusions:Microecological preparations play an important role in the treatment for diarrhea Proper use of this kind of drug could contribute to the recovery from diarrhea But it is not reasonable to use combinations of different microecological preparations blindly
出处
《中国微生态学杂志》
CAS
CSCD
2003年第2期102-104,共3页
Chinese Journal of Microecology
