摘要
目的 研究以导管为基础192Ir放射性线源治疗冠状动脉再狭窄时,放射源与靶区错位对靶区边缘剂量的影响。方法 用AAPM60,43号报告推荐的公式计算剂量分布。结果 放射源与靶区错位1.1 mm时,靶区边缘剂量最大可降低53.9％,受影响范围为6 mm;放射源与靶区错位5 mm时,靶区边缘剂量最大可降低565.8％,受影响范围为9 mm。结论 错位将导致一端靶区边缘的剂量降低。
Objective To investigate the effect on the dose distribution of source position displacement with the target region margin in catheter-based 192Ir line source endovascular brachytherapy. Method Dose rate distribution along longitudinal axes was estimated by the formula recommended by AAPM No.60 and No.43. Results In the two cases of source displacement (1.1 and 5 mm) doses of target region margin was decreased dramatically (at most 53.9% and 565.8% respectively) were compared to that of no source displacement, and the affected range was 6 mm and 9 mm respectively. Conclusion Source displacement will lead to the decrease of dose in target region margin.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2003年第2期193-196,共4页
Acta Academiae Medicinae Sinicae
基金
国家自然科学基金(30170233)资助
