期刊文献+

神经生长因子的研究 被引量:9

暂未订购
导出
摘要 神经生长因子 (NGF)在神经元的发育、轴突的生长、递质的合成及细胞的凋亡等阶段均起重要作用。NGF来源十分广泛 ,可以由不同来源的细胞分泌 ,其结构已得到证实 ,构效关系也已研究得较为清楚。NGF的作用主要通过与受体蛋白结合而发挥作用。NGF神经生物学的研究发展迅速 ,研究证明NGF能够促进神经细胞的再生 ,对中枢和周围神经的损伤均有保护和恢复的作用。
出处 《海峡药学》 2003年第2期8-10,共3页 Strait Pharmaceutical Journal
  • 相关文献

参考文献16

  • 1邓小华,罗学港.神经生长因子受体TrkA在中枢神经系统的表达、分布和作用[J].国外医学(神经病学.神经外科学分册),2000,27(1):52-55. 被引量:3
  • 2Ibanez CF. Strcture-function relationships in the neurotrophin family,J Neurobiol 1994,25 : 1349~1361.
  • 3Lipps BV. Isolation of nerve growth factor(NGF)from human body fluids;saliva,serum and urine:comparison between cobra venom and cobra serum NGF. J Nat Toxins,2000~9(4): 349~356.
  • 4Lipps BV. Isolation and characterization of nerve growth factor(NGF)excreted from cultured eukaryotic cells,J Nat Toxins 2001 ;(10)3 : 213~9.
  • 5Maness LM et al. The neurotrophins and their receptors:structure,function and neuropathology. Neuroscl Biobehavi Rew 1994~ 18:143~159.
  • 6Greene LA et al Early events in neurotrophin sigoalling via Trk and p75 receptors. Curr Opin Neurobiol 1995;5: 579~587.
  • 7Anton ES et al. Nerve growth factor and its low-affinity receptor promote Schwann cell Migration. Proc Natl Acad Sci U S A,1994;91(7) : 2795~2799.
  • 8Hantzopoulos PA et al. The low affinity NGF receptor, p75, can collaborate With each of the Trks to potentiate functional responses to the neurotrophins. Neuron 1994;13(1): 187~201.
  • 9Davies AM, Neural development. Chemoattractants for navigating axons. Curr Biol 1994,4(12): 1142~1145.
  • 10Alderson RF et al, Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron 1990~5(3): 297~306.

二级参考文献10

  • 1Steining TL,et al. Brain Research . 1993
  • 2Cooper JD,et al. Neuroscience . 1994
  • 3Boissiere F,et al. Experimental Neurology . 1997
  • 4Masami K,et al. Neuroscience Letters . 1994
  • 5Li Yiwen,et al. The Journal of Neuroscience . 1995
  • 6Large TH,et al. Science . 1986
  • 7Klein R,et al. Cell . 1991
  • 8David M,et al. The Journal of Neuroscience . 1995
  • 9Hsiang J,et al. Neuroscience . 1988
  • 10Gibbs RB. Experimental Neurology . 1998

共引文献2

同被引文献108

引证文献9

二级引证文献39

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部