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抑癌基因p16的研究进展 被引量：3

Research Advances on Tumor Suppressor Gene p16
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摘要 p16是近年来确定的多肿瘤抑制基因,它对细胞周期的负调控作用尤为重要,其突变或缺失会导致对细胞分裂调控的丧失和紊乱,导致细胞的异常增殖,最终形成肿瘤.该基因在各种肿瘤中的作用,目前正越来越引起人们的重视. The p16 gene is multiple tumor suppressor gene (MTS1) determined in recent years. It is important to the negative regulation of cell cycle. Mutation or deletion of p16 will lead to loss and confusion of regulation to cell division, and induce abnormal multiplication of cell and form tumor. At present, much attention is paid to the function of p16 gene in all kinds of tumors.
作者 曹原 刘志学
机构地区 上海大学生命科学学院
出处 《上海大学学报（自然科学版）》 CAS CSCD 2003年第1期55-60,共6页 Journal of Shanghai University:Natural Science Edition
关键词 P16基因 抑癌基因 细胞周期调控 肿瘤治疗 基因治疗 分子机制 细胞分裂调控 p16 gene tumor suppressor gene cell cycle regulation tumor gene treatment
分类号 R730.231 [医药卫生—肿瘤] R394 [医药卫生—医学遗传学]
  • 相关文献

参考文献34

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共引文献68

同被引文献26

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引证文献3

二级引证文献6

上海大学学报（自然科学版）
2003年 第1期

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