摘要
消化性溃疡、急性胃黏膜病变是临床常见病、多发病 ,中药防治胃黏膜损伤有其自身特点及优势。近年来许多学者在此领域作了大量研究工作 ,发现并证实许多中药单味药及复方制剂具有明显的胃黏膜保护作用 ,阐明了中药可通过如下多种途径及机制达到防治胃黏膜损伤的作用 :抗胃酸、胃蛋白酶 ;强化胃黏膜、黏液屏障 ;改善调节胃黏膜血流 ;诱导胃黏膜内源性保护因子的合成和释放 ,增强胃黏膜细胞保护作用 ;抗自由基损伤等。
Peptic ulcer and acute gastric mucosal lesion are commonly and frequently encountered diseases.Traditional Chinese medicines (TCM) have their own trait and predominance in treating and preventing gastric mucosal injury.In recent years,many scholars have been engaged in this research.Their works proved that many single and complex Chinese herbs had marked protective effect on gastric mucosal injury.Furthermore,they elucidated that TCM was able to prevent and treat gastric mucosal injury through different mechanisms,which included resisting gastric acid and pepsin; enforcing the gastric mucosal mucus barriers;improving and modulating the blood circulation of gastric mucosa;inducing the generation and release of gastric mucosal endogenous protective factors,promoting gastric mucosal cytoprotective effect;clearing oxygen free radical.All these research works provide scientific proof of TCM for the clinical application in anti-gastric mucosal injury.
出处
《东南大学学报（医学版）》
CAS
2003年第2期129-132,共4页
Journal of Southeast University(Medical Science Edition)
关键词
中药
胃黏膜
保护作用
实验研究
traditional Chinese medicines
gastric mucosa
protective effect
experimental study
