摘要
观察干地黄和熟地黄水煎剂对幽门结扎大鼠胃酸分泌及胃溃疡形成的影响。以１００％或５０％的于地黄和熟地黄液２．０ｍｌ分别注入大鼠十二指肠内，均明显抑制胃液量、总酸度及总酸排出量，且有一定的量效关系；并能减少胃溃疡的发生率和溃疡数，溃疡抑制率干地黄为６９．６％，熟地黄为８９．２％。熟地黄的抑酸作用强于干地黄。
Decoction(100%or50%)of the dry of steamed RR was injected respec-tivelv into the duodenum(2.0ml/rat)to study the enects on gastric acid secretion and ulcer for-mation in the pylorus ligated rats.In a dose一dependent manner,the volume of gastric juice,totalaciditv and total acid output were inhibited significantly. The incidence and the number of erosionswere decreased as well.The inhibitory rate of dry rcots was 69.6% of the steamed ones 89.2%.The inhibitory action of the steamed roots of RR on gastric acid secretion is stronger than that ofthe dry ones.
出处
《湖南中医学院学报》
1996年第2期49-51,共3页
Journal of Hunan College of Traditional Chinese Medicine
基金
CMB基金资助课题
关键词
地黄
中药药理学
胃酸
胃溃疡
Rehmanniae/pharmacology
gastric acid/drug action
gastric ulcer/chem-ical induction
model,biology.
