摘要
目的 探讨静脉导管的血流流速曲线在筛选和协助早期诊断胎儿先天性心脏病中的临床意义。方法 应用彩色多普勒超声诊断系统检测 2 40例 14～ 41孕周的正常胎儿和 2 0例先天性心脏病胎儿的静脉导管血流流速曲线 ,并计算静脉导管血流阻力指数、搏动指数及心室收缩期峰值速度与心房收缩期最大流速比值。结果 ①正常胎儿静脉导管的血流流速曲线呈特殊的波形 :心室收缩期波峰S、心室舒张期波峰D和心房收缩期波谷A ,前向血流持续整个心动周期 ;② 2 0例先天性心脏病胎儿中 8例静脉导管的A波出现反转 ,9例A波降低或缺失 ,3例无明显变化。先天性心脏病胎儿组静脉导管血流指数较胎龄相匹配的正常胎儿组增高 ,两组比较差异有显著性意义 (P <0 .0 5 )。结论 彩色多普勒超声检测胎儿静脉导管的血流流速曲线可筛选或协助早期诊断胎儿先天性心脏病。
Objective To investigate the clinical significance of Doppler flow waveform of ductus venosus (DV) in screening of fetal cardiac malformation.Methods Color Doppler ultrasonography was used to study DV flow in 240 normal fetuses and 20 fetuses with cardiac malformation that were screened out from the high-risk fetuses with congenital heart disease (CHD).Results ① The normal Doppler flow waveform of the DV was a characteristic triphasic pattern with forward flow during cardiac cycle,reflecting ventricular systole (S),ventricular diastole (D) and atrial systole (A).② In the group of 20 fetuses with cardiac malformation,eight had reverse flow and nine had decreased or absent flow during atrial contraction,the indices of the DV in fetuses with cardiac malformation were higher than those in gestational age-matched normal fetuses ( P < 0.05 ).Conclusions Doppler ultrasonographic detection of DV blood flow will be useful as a new prospective technique in screening of fetal cardiac malformation.
出处
《中华超声影像学杂志》
CSCD
2003年第3期158-161,共4页
Chinese Journal of Ultrasonography
