摘要
目的 :调查分析各科手术住院病人抗菌药物应用情况及合理性。方法 :根据事先设计好的调查表 ,按统一方法、标准和内容 ,对 4 38例手术病人出院病历作回顾性调查。结果 :外科住院病人抗菌药物总应用率为 94 .3% ,其中单用、二联、三联及以上抗菌药物者分别为 35 .1% ,2 7.1%和 37.8% ;预防性抗菌药物总的应用率为 87.4 % ,其中Ⅰ类切口应用率为 97.1% ,Ⅱ～Ⅲ类切口为 96.3% ;在术前应用抗菌药物为 2 6.4 % ,在术后抗菌药物应用中 ,≤ 3d者为 4 .7% ,≤ 7d者为 37.4 % ,>7d者占5 7.9% ;抗菌药物应用合理为 4 4 .8% ,基本合理为2 8.3% ,不合理为 2 6.9%。结论 :加强抗菌药物的应用管理 ,制定使用规范 ,重视病原检查 ,依据用药指征、药敏试验结果、药动学、溶媒量等选药 ,以减少耐药菌株产生 。
AIM:To investigate and analyse the use and rationality of antimicrobial agents in the surgical departments inpatients. METHODS:A retrospective investigation was made in 438 operational patients discharged from hospital depending on the designed table and uniform method, standard and content. RESULTS:The total utilization ratio of antimicrobial agents by the in patients of surgical departments reached 94.3 % . Among it, that of using antimicrobial agenls singly, doubly, trebly and more was 35.1 % , 27.1 % and 37.8 % . The preventive use ratio of it was 87.4 % , including 97.1 % for I kind incisions, 96.3 % for Ⅱ Ⅲ kind incisions. The administration of it before the operation was 26.4 % , in the administrations of it after the operations, it was 4.7 % less than three days, 37.4 % less than seven days, 57.9 % more than seven days. It was 44.8 % that was rational use of antimicrobial agents, 28.3 % was radical rationality and 26.9 % was irrational. CONCLUSION:Strengthening the management and working out regulations for the use of antimicrobial agents, stressing etiological examinations and utilization according to the indications, the results of drug sensitive tests, pharmacodynamics and so on are of great significance to the reduction of the occurrence of resistant strains and the infection.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2003年第3期184-187,共4页
Chinese Journal of New Drugs and Clinical Remedies
关键词
抗感染药
头孢菌素类
外科手术
anti infective agents
cephalosporins
surgery, operative
