摘要
目的 比较丁咯地尔与维脑路通对急性脑梗死的临床疗效。方法 将 86例急性脑梗死患者 ,随机分为丁咯地尔组4 6例及维脑路通组 4 0例 ,应用神经功能缺损评分标准评定临床疗效 ,并观察用药前后血液流变学变化。结果 治疗前后比较 ,神经功能缺损评分均有降低 ,丁咯地尔组有效率 86 .2 %,显效率领 6 5 .2 %,对照组有效率 6 2 .3%,显效率 7.5 %,两组比较有效率差异显著 (P <0 .0 5 ) ,显效率比较差异非常显著 (P <0 .0 1)。用药后丁咯地尔组全血粘度降低 ,与治疗前比差异显著 (P <0 .0 5 ) ,对照组治疗后相比差异不显著。结论 丁咯地尔有多项药效 ,是治疗急性脑梗死的安全有效药物。
Objective To compare the clinical efficacy of buflomedil hydrochlruide and venoruton in treating acute cerebral infarchion.Methods 86 patients with acute cerebral infaction were d into twogroups randomly:Buflomedil group(46 cases) and Venoruton hroup(40 cases).Before and after therapy,the scores of clinical nerve function deficiency(CNFDS) were evaluated by senior doctor,and hemorheological indexes were determined.Results The scores of neurologyc function deficits in both groups were lower that before tratment.The cure rate and the marked improvement rate in Buflomedil grup were 86.2% and 65.2% orespectively, It was 62.3% and 27.5% in Venoruton group. There were great differences between the two groups in the cure rate ( P<0.05) and the marked impuocement rate( P<0.01).After Buflomedil therapy,the cases'blood viscosity obviousy decreased than that before( P<0.05).It hadn't obvious changes in Venoruton group ( P>0.05) .Conclusion Butflonedil,having many potecy properties,is an effective and safe medicine in the treatmint of acute cerebral infarction.
出处
《临床军医杂志》
CAS
2003年第1期14-15,共2页
Clinical Journal of Medical Officers
关键词
急性脑梗死
丁咯地尔
疗效观察
acute cerebral infarction
buflomedil hydrochlouide
observation of the clinical efficacy
