摘要
目的 :了解妊娠晚期孕妇血浆同型半胱氨酸 (Hcy)含量与孕妇平均动脉压的关系。方法 :采用荧光标记免疫检测法检测 6 7例正常晚孕妇女和 15例正常非孕妇女 (对照组 )血浆Hcy的含量。结果 :正常晚孕组血浆同型半胱氨酸含量 7 89± 3 2 7μmol/L ,明显高于正常对照组 6 6 3± 1 0 7μmol/L ,P <0 0 5 ;正常晚孕妇女组血浆Hcy含量与平均动脉压呈正相关 ,P <0 0 5 ;对照组妇女Hcy含量与平均动脉压呈正相关趋势 ,但无统计学意义 ,P >0 0 5。结论 :测定妊娠晚期孕妇血浆Hcy含量可以为孕期补充叶酸提供指导 ,有重要的临床意义。
Objective:To investigate the relation between plasma homocysteine(Hcy)concentration and mean arterial pressure(MAP)in the third trimester of pregnant women.Methods:Fifteen normal non-pregnant women and 67 normal pregnant women in the third trimester with prenatal check-up and childbirth in our hospital between December 1998 and December 1999 were enrolled in our study.Fluoroimmunoassay(FIA)was employed to measure the levels of plasma Hoy.MAP=diastolic pressure+(systolic pressure-diastolic pressure)/3.Results:The level of plasma Hcy in normal pregnant group was remarkably higherthan that in non-pregnant group(7.89±3.27unol/L vs 6.63±1.07umol/L,p<0.05).A positive correlation was observeb between plasma Hcy levels and MAP in pregnant group(P<0.05).There was also a positive correlation between plasma Hcy levels and MAP in non-pregnant group(P>0.05)but it has no statistic significance.Conclusion:Determination of the plasma Hcy levels in the third trimester of pregnant women can provide guidance with folic acid complemant during pregnancy,which is not only good for the growth development of fetus but also might prevent pregnancy-induced hypertension syndrome.It has important eugenics significance.
出处
《西南国防医药》
CAS
2003年第1期33-35,共3页
Medical Journal of National Defending Forces in Southwest China
基金
云南省自然科学基金资助
NO :98C0O33Q
