摘要
目的通过动态观察血浆同型半胱氨酸(homocysteine,Hcy)含量的变化了解妊娠期高血压疾病(hypertensive disorder complication pregnancy,HDCP)的预后。方法选择妊娠期高血压疾病子癇前期患者133例,其中轻度子癇前期104例、重度子癇前期29例,观察治疗前后血浆同型半胱氨酸的变化。结果轻度子癇前期78例、重度子癇前期4例患者在治疗前后血浆同型半胱氨酸无变化(P>0.05),临床治疗有效,妊娠得于持续。轻度子癇前期26例、重度子癇前期25例患者血浆同型半胱氨酸明显升高(P<0.05,P<0.01),治疗效果差,病情加重,最终需终止妊娠。结论通过动态观察血浆同型半胱氨酸的变化可指导妊娠期高血压疾病的治疗和了解其预后。
Objective： To explore the prognosis of hypertensive disorder complication pregnancy by dynamic observation of the variability of plasmic homocysteine. Methods： 133 patients of pre - eclampsia （ 104 cases were mild and 29 were severe） were studied. The variability of plasmic homocysteine after treatment was observed. Results ： There was no significant change of plasmic homocysteine in 78 mild cases and 4 severe cases （ P 〉 0. 05 ）. The clinical treatment was effective, and the pregnancy continued. But there were significant elevation of plasmichomocysteine in 26 mild cases and 25 severe cases （ P 〈0. 05, P 〈0. 01 ）. The efficacy of treatment was bad, the patient＇s condition was exacerbated, and the pregnancy had to be terminated. Conclusion： Dynamic observation of the variability of plasmic homocysteine can be used to guide the treatment and explore the prognosis of hypertensive disorder complication pregnancy.
出处
《中国优生与遗传杂志》
2007年第4期31-32,共2页
Chinese Journal of Birth Health & Heredity
基金
佛山市卫生局资助项目
项目编号2004235
