摘要
研究了动物源性食品中磺胺嘧啶、磺胺二甲嘧啶、磺胺间甲氧嘧啶、磺胺喹啉药物残留的提取、净化和高效液相色谱分析条件 ,建立了高效液相色谱法同时测定动物源性食品中磺胺类药物残留的方法 ,该法检出限为0.010×10-6～0.020×10-6(w) ,添加回收率为71 %～83 %。
A method for the simultaneous determination of sulfonamides veterinary drugs residues in food of animal origin, including sulfadiazine, sulfamonomethoxine, sulfaquinoxaline and sulfadimidine, was established by HPLC in a column of Hypersil C18(250 mm×4.6 mm) with a mobile phase consisting of 1% acetic acid-methanol(65∶35 by volume). The drugs in homogenized tissue samples were abstracted by dichloromethane extraction coupled with solid phase extraction of HLB column. The chromatographic conditions were optimized. The detection limits of 0.010×10-6～0.020×10-6(w) and recoveries of 71%～83% were obtained for the method.
出处
《分析测试学报》
CAS
CSCD
北大核心
2003年第1期94-96,共3页
Journal of Instrumental Analysis
