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液相色谱-串联质谱技术在食品药品安全分析领域的应用 被引量:6

Application of liquid chromatography-tandem mass spectrometry in food and drug safety analysis
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摘要 液相色谱(liquid chromatogram,LC)在分离能力、灵敏度和专属性等方面有着巨大优势,与质谱(mass spectrometry,MS)联用后可以展现出强大的定性、定量分析能力,并已经在农兽药残留、非法添加、有毒物质研究等各领域得到广泛应用。本文对液相色谱-串联质谱(liquid chromatography-tandem mass spectrometry,LC-MS/MS)技术在食品相关国家标准,如农残、兽残、食品接触类材料,及《中华人民共和国药典(2015版)》中的应用进行了简单介绍,并介绍了本部门在食品安全、药品安全、食品接触类塑料制品残留物分析等领域取得的工作进展。 Liquid chromatography (LC) has great advantages in the capacity of separation, sensitivity and specificity, and mass spectrometry (MS) can be combined to show strong qualitative and quantitative analysis capabilities, and they have been found widespread application in the food safety analysis, particularly in the analysis of pesticide residues, veterinary drug residues, illegal additives and toxic substances. This paper reviewed the application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) in the fields of pesticide residues, veterinary drug residues and food contact materials of national food standards and pharmacopoeia of China, and introduced the research progress of food safety, drug safety and residues in food plastic materials of our group.
作者 勾新磊 刘伟丽 高峡 周明强 赵新颖 GOU Xin-Lei LIU Wei-Li GAO Xia ZHOU Ming-Qiang ZHAO Xin-Ying(Beijing Centre for Physical and Chemical Analysis, Beijing Key Laboratory of Organic Materials Testing Technology & Quality Evaluation, Beijing 100089, China Beijing Academy of Science and Technology Key Laboratory of Analysis and Testing Technology, Beijing 100089, China)
出处 《食品安全质量检测学报》 CAS 2016年第11期4283-4288,共6页 Journal of Food Safety and Quality
基金 北京市科学技术研究院创新团队计划项目(IG204605N) 北京市科学技术研究院萌芽计划项目(2015-02)~~
关键词 超高效液相色谱 质谱 食品安全 药品安全 ultra performance liquid chromatography mass spectrometry food safety drug safety
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