摘要
目的 探讨交通警察所接触有害因素及体内脂质过氧化和抗氧化水平。方法 对 1 70名交通警察 (接触组 )及 1 0 8名不接触有害因素作业的健康人员 (对照组 )测定血清中超氧化物歧化酶 (SOD)活性、谷胱甘肽过氧化物酶 (GSH Px)活性、血清丙二醛 (MDA)的含量并测定环境有害因素 [粉尘、一氧化碳 (CO)及氮氧化物 ]的浓度。结果 接触组工作场所空气中粉尘、CO、氮氧化物浓度均高于对照组 ,差异有显著意义 (P <0 0 1 )。接触组体内SOD和GSH Px活性明显低于对照组 ,差异有显著意义 (P <0 0 1 ) ;而血清中MDA含量高于对照组 ,差异有显著意义 (P <0 0 1 )。
Objective In order to explore the harmful factors exposed by the traffic policemen and the content of lipid peroxidation and antioxidation in their bodies. Methods The activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH Px), and the content of malondialdehyde (MDA) were determined in the serum of 170 traffic policemen and 108 healthy persons without exposure to any harmful factors. The harmful factors in the environment were determined (the concentration of the dust, carbon monoxide and nitrogen oxide). Results The concentration of the dust, carbon monoxide and nitrogen oxide in the traffic policemen's environment were higher than those in the control with significant difference( P <0 01). The activities of SOD and GSH Px in the bodies of the traffic policemen were less than that of the control and also with significant difference( P <0 01), while the content of MDA in traffic policemen's serum was significantly higher than that in the control( P <0 01). Conclusion The harmful factors to which the traffic policemen were exposed might lead to the rise of lipid peroxidation and the decline of the function of antioxidation in their bodies.
出处
《中国职业医学》
CAS
北大核心
2002年第6期16-18,共3页
China Occupational Medicine
