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胆红素的神经毒性作用 被引量:4

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摘要 脑出血后血肿周围脑组织水肿的形成是脑出血后继发脑损伤的一个重要因素。脑水肿形成的机制仍有多处需待阐明。研究证实 ,水肿的形成涉及血肿代谢产物如铁离子、血红素、CO等的毒性作用。
作者 吴刚
出处 《中国临床神经科学》 2002年第4期420-423,共4页 Chinese Journal of Clinical Neurosciences
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  • 1丁力,彭巧玲,高球仙,罗建清,孙振球.长沙市区10万人群脑卒中流行病学调查[J].湖南医科大学学报,1995,20(3):219-222. 被引量:14
  • 2Katoh R, Kashiwmnata S, Nrwa F. Studies on cellular toxicity of bilirubin:Effect on the carbohydrate metabolism in the young rat brain [J]. Brain Res, 1975; 83: 81-92
  • 3Semba RK. Studies on cellular toxicity of bilirubin: Effect on brain glycolysis in the young rat[J]. Brain Res, 1976; 113: 339-346
  • 4lyes NK, Bolas NM, Gardiner RM,The effects of bilirubin on brain energy metabolism during hyperosmolar opening of the blood-brain barrier: An in vivo study using 31 p nuclear magnetic resonance spectroseopy[J]. Pediatr Res, 1989;26:356-361
  • 5Wennberg RP, Johansson BB, Folbergrova J, et al. Bilirubin-induced changes in brain energy metabolism after osmotic opening of the blood-brain barrier[J]. Pediatr Res. 1991 ;30:473-478
  • 6Hoffman DJ,Zanelli SA, Kubin J, et al. The in vivo effect of bilirubin on the N-methyl-D-aspartate receptor/ion channel complex in the brains of newborn piglets[J]. Pediatr Res, 1996;40:804-808
  • 7Sano K, Nakamura H, Matsuo T, et al. Mode of inhibitory action of bilirubin on protein kinase C[J]. Pediatr Res, 1985;19:587-590
  • 8Amit Y, Boneh A. Bilirubin inhibits protein kinase C activity and protein kinase C-mediated phosphorylation of endogenous substrates in human skin fibroblasts[J] .Clin Chim Acta,1993;223:103-111
  • 9Hansen TW, Mathiesen SB, Walaas SI. Bilirubin has widespread inhibitory effects on protein phosphorylation[J]. Podiatr Res, 1996;39:1072-1077
  • 10Hansen TW, Mathiesen SB, Walaas SI. Modulation of the effect of bilirubin on protein phosphorylation by lysine-containing peptides[J]. Podiatr Res,1997;42:615-617

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