摘要
用单克隆抗体和放射免疫法测定了14例正常人静止型和ADP—活化型血小板表面颗粒蛋白(GMP—140)分子数,结果表明,血小板活化后GMP叫40分子数明显增高。
By using 125I-SZ51,a monoclonal antibody specific for human platelet GMP-140, and radioimmunoassay, the molecular numbers of GMP-140 on the surfaces of resting and ADP-activated platelets from fourteen normal human subjects was measured. The results showed that the molecular number of GMP-140 was significantly increased after the platelets were activated. It was suggested that the method described may be useful to assess the degree of platelet acivation.
出处
《第一军医大学学报》
CSCD
1992年第2期110-111,共2页
Journal of First Military Medical University
基金
国家自然科学基金资助项目
关键词
血小板
膜蛋白
放射免疫法
抗体
platelet
GMP-140
radioimmunoassay
monoclonal antibody
