摘要
目的 :探讨胃肠道腺癌细胞核DNA含量与腺癌组织学分类、分级及其预后的关系。方法 :应用国产的CMIAS 真彩色医学图象分析系统 ,对 93例胃腺癌 ,6 3例肠腺癌癌细胞核进行DNA测定。结果 :腺癌细胞核的DNA含量相对倍体均量 (μ值 )与组织学分级有统计学意义 (P <0 0 5 )。 结论 :胃肠道腺癌细胞DNA含量的变化 ,可作为反映肿瘤增殖能力的主要生物学指标。肿瘤的恶性程度与DNA含量密切相关。但粘液腺癌与粘液细胞癌有其特殊性 。
Objective:To evaluate the relationship between DNA content of adenocarcinoma nuclei of gastrointestinal tract and classification and grading in adenocarcinoma histology, and the prognosis.Methods:The nuclei DNA in 93 cases of gastric adenocarcinoma and 63 cases of enteral adenocarcinoma were detected with Colour Medical Cell Image Analysis System (CMIAS) made in China.Results:The μ value of the adenocarcinoma nuclei DNA and the histological grading were statistically significant ( P <0 05). Most of the nuclei DNA in the special types of adenocarcinoma (mucinous adenocarcinoma and carcinoma mucocellulare) were doubleploid, and the μ value between them was not different significantly ( P >0 05).Conclusion:Changes of adenocarcinoma nucleus DNA content of gastrointestinal tract were main biologic indexes of tumor multiplication potentiality. Malignant degree of tumor was closely relatd to the DNA content. Mucinous adenocarcinoma and
出处
《临床肿瘤学杂志》
CAS
2002年第6期411-412,共2页
Chinese Clinical Oncology
关键词
胃肠道腺癌
DNA
定量分析
临床意义
carcinoma mucocelluare had their specificity, to which much attention should be paid.Gastrointestinal tract
Adenocarcinoma
DNA
Quantitative analysis
