摘要
建立气相色谱-质谱联用(GC-MS)同步检测儿童指画颜料中六氯苯(HCB)、9种多氯联苯(PCBs)及苯并[α]芘(B[α]P)的方法,采用涡旋振荡无水硫酸钠脱水(静置4 h),以体积比1∶1的正己烷和丙酮为提取溶剂,超声萃取3次;通过DB-5MS色谱柱分离,采用SIM模式检测。研究结果表明,11种目标化合物在0.1~5.0 mg/L范围内线性关系良好(R^(2)≥0.9988),检出限0.002~0.010 mg/kg,定量限0.005~0.050 mg/kg;三个添加水平下的加标回收率为90.7%~109.7%,精密度RSD≤9.59%。应用该方法检测35批次市售样品,结果显示40%样品中存在目标化合物。该方法高效、准确、安全,可为我国儿童指画颜料安全性评价、标准制定及市场监管提供技术支撑和理论依据。
A method is established for the simultaneous determination of hexachlorobenzene(HCB),9 polychlorinated biphenyls(PCBs),and benzo[α]pyrene(B[α]P)in children's finger paints by gas chromatography-mass spectrometry(GC-MS).The pretreatment process is defined as follows:dehydrated with anhydrous sodium sulfate by vortexing and standing for 4 h,and extracted three times with n-hexane to acetone of volume ratio of 1:1;separated by DB-5MS column and detected in SIM mode.The results show that the 11 target compounds have good linearity in the range of 0.1-5.0 mg/L(R^(2)≥0.9988),with detection limits of 0.002-0.010 mg/kg and quantification limits of 0.005-0.050 mg/kg.The recovery rates at three spiked levels are 90.7%-109.7%,and the precision RSD is≤9.59%.Through this method,35 batches of commercial samples are tested,and it is found that 40%of the samples contain target compounds.This method is efficient,accurate,and safe,and can provide technical support for the safety evaluation,standard formulation,and market supervision of children's finger paints in China.
作者
董亚楠
范雪婵
吴涛
梁青
聂佳佳
DONG Yanan;FAN Xuechan;WU Tao;LIANG Qing;NIE Jiajia(Hebei Research Institution for Product Quality Supervision and Inspection,Shijiazhuang 050227,Hebei,China;Hebei Province Drug Professional Inspector Crops(North District),Qinhuangdao 066000,Hebei,China)
出处
《印染》
北大核心
2026年第3期72-75,89,共5页
China Dyeing and Finishing
基金
河北省市场监督管理局科研计划项目(2023ZD08)。
关键词
测试
指画颜料
六氯苯
多氯联苯
苯并[α]芘
气相色谱-质谱联用法
testing
finger paint
hexachlorobenzene
polychlorinated biphenyl
benzo[α]pyrene
gas chromatography-mass spectrometry
