摘要
在航天飞行任务中,微重力与太空辐射等环境因素可对航天员免疫功能产生深远影响,且部分效应在返回地面后仍持续存在。单核/巨噬细胞作为先天免疫的核心组成部分,其功能状态与航天员健康密切相关。本文聚焦单核/巨噬细胞这一关键免疫群体,系统回顾其在航天特因环境(微重力、辐射)及返回恢复过程中的动态变化与机制,旨在为保障深空探索中航天员免疫健康提供依据,并为地面免疫学研究提供参考。
During spaceflight,environmental factors such as microgravity and space radiation can profoundly affect astronauts’immune function,with some of these effects persisting even after returning to Earth.As core components of innate immune system,monocytes and macrophages are closely linked to astronaut health.This paper focuses on monocytes and macrophages,systematically summarizing their dynamic changes and underlying mechanisms under space-specific conditions(microgravity,radiation)and during post-flight recovery,aiming to provide a scientific basis for safeguarding immune health in deep-space exploration and to offer insights for terrestrial immunological research.
作者
柳欣
刘庆华
LIU Xin;LIU Qinghua(The Second Clinical Medical Faculty,Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Department of Respiratory and Critical Care Medicine Subject,East Hospital Affiliated to Tongji University,Shanghai 200120,China)
出处
《航天医学与医学工程》
2026年第1期88-94,共7页
Space Medicine & Medical Engineering
