摘要
目的探讨中晚期结直肠癌患者生命质量的影响因素并分析各因素之间的影响路径。方法采取便利抽样法选取2020年1月—2024年1月在江西省肿瘤医院接受治疗的中晚期结直肠癌患者。收集患者的一般临床资料,采用癌症治疗功能评价系统(functional assessment of cancer therapy-colorectal,FACT-C)、疾病获益感量表(benefit finding scale,BFS)、心理弹性量表(10-item connor-davidson resilience scale,CD-RISC-10)、中文版癌症赋权问卷(cancer empowerment questionnaire,CEQ)对患者进行调查。结果共发放问卷215份,有效回收问卷200份,有效回收率为93.02%。结构方程模型显示,癌症转移、临床分期、BFS评分、CD-RISC-10评分、中文版CEQ评分均对中晚期结直肠癌患者生命质量有直接效应,其路径系数为-11.398、-6.006、0.448、0.875、0.215;其中临床分期、癌症赋权、疾病获益感均可间接影响生命质量,其中“临床分期→癌症转移→生命质量”的中介路径系数为-2.108;“癌症赋权→疾病获益→生命质量”的中介路径系数为0.090;“癌症赋权→心理弹性→生命质量”的中介路径系数为0.056;“癌症赋权→疾病获益→心理弹性→生命质量”的中介路径系数为0.039(均P<0.05)。结论中晚期结直肠癌患者生命质量水平受癌症转移、临床分期、疾病获益感、心理弹性、癌症赋权感知等因素影响,医护人员可以此筛选出受影响较大的患者并制定相应的干预方案,帮助患者改善生命质量与预后质量。
Objective To explore the influencing factors of quality of life in patients with mid-to-late stage colorectal cancer and to analyze the influence pathways among these factors.Methods A convenience sampling method was conducted to select patients with mid-to-late stage colorectal cancer who received treatment at Jiangxi Cancer Hospital from January 2020 to January 2024.General clinical data of the patients were collected.The functional assessment of cancer therapy-colorectal(FACT-C),benefit finding scale(BFS),10-item connor-davidson resilience scale(CD-RISC-10),and cancer empowerment questionnaire(CEQ)were used to conduct surveys among the patients.Results A total of 215 questionnaires were distributed in this study,and 200 valid questionnaires were collected,with an effective recovery rate of 93.02%.Structural equation modeling showed that cancer metastasis,clinical stage,BFS score,CD-RISC-10 score,and CEQ score all had direct effects on the quality of life in patients with mid-to-late stage colorectal cancer,with path coefficients of-11.398,-6.006,0.448,0.875,and 0.215,respectively.Among them,clinical stage,cancer empowerment,and benefit finding could all indirectly affect quality of life,which the mediating path coefficients were as follows:"clinical stage→cancer metastasis→quality of life"was-2.108;"cancer empowerment→benefit finding→quality of life"was 0.090;"cancer empowerment→psychological resilience→quality of life"was 0.056;"cancer empowerment→benefit finding→psychological resilience→quality of life"was 0.039(all P<0.05).Conclusion The level of quality of life in patients with mid-to-late stage colorectal cancer is influenced by factors such as cancer metastasis,clinical stage,benefit finding,psychological resilience,and cancer empowerment.Healthcare workers can use these findings to identify patients who are more affected and develop corresponding intervention plans to help improve patients'quality of life and prognosis.
作者
万远婷
周珊珊
涂店红
冯丽萍
刘童新
仇芬
WAN Yuanting;ZHOU Shanshan;TU Dianhong;FENG Liping;LIU Tongxin;QIU Fen(Jiangxi Cancer Hospital,Nanchang 330029,Jiangxi,China;The First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi,China)
出处
《护士进修杂志》
2026年第1期41-47,共7页
Journal of Nurses Training
基金
江西省中医药管理局科技计划项目(编号:2020A0132)。
关键词
结直肠癌患者
生命质量
结构方程模型
影响路径
护理
colorectal cancer patients
quality of life
structural equation modeling
influence pathways
nursing
