摘要
目的探讨气压联合综合淋巴消肿疗法(complete decongestive therapy,CDT)治疗宫颈癌放疗淋巴水肿的临床疗效。方法选取2022年7月至2024年7月于赣州市肿瘤医院就诊的60例宫颈癌放疗后淋巴水肿患者作为研究对象,采用随机数字表法分为治疗组与对照组,各30例。治疗组接受气压联合CDT治疗,对照组接受常规脱水消肿药物治疗。比较两组淋巴水肿分期、视觉模拟评分法(visual analogue scale,VAS)评分、肢体周径差、静脉平均血流速度及中文版癌症治疗功能评价系统量表(functional assessment of cancer therapy,FACT-G)评分。结果治疗14 d后,治疗组VAS评分低于对照组,肢体周径差小于对照组,静脉平均血流速度快于对照组,差异有统计学意义(P<0.05)。治疗14 d后,治疗组淋巴水肿分期优于治疗前及对照组,差异有统计学意义(P<0.05),对照组与治疗前比较差异无统计学意义。治疗14 d后,治疗组生理状况、社会/家庭状况、情感状况、功能状况评分均高于对照组,差异有统计学意义(P<0.05)。结论气压联合CDT治疗宫颈癌放疗后淋巴水肿患者的临床疗效显著,可有效促进滞留组织淋巴液回流,并减轻肢体的肿胀和疼痛程度,改善患者的生命质量。
Objective To investigate the clinical efficacy of air pressure combined with complete decongestive therapy(CDT)in the treatment of lymphedema in cervical cancer radiotherapy.Methods 60 patients with lymphedema after radiotherapy for cervical cancer in Ganzhou Tumor Hospital from July 2022 to July 2024 were selected as the research subjects,and they were divided into the treatment group and the control group according to random number table method,with 30 cases in each group.The treatment group was treated with air pressure combined with CDT,and the control group was treated with conventional dehydration and detumescence drugs.The lymphedema stage,visual analogue scale(VAS)score,limb circumference difference,mean venous blood flow velocity and Chinese version of functional assessment of cancer therapy(FACT-G)score were compared between the two groups.Results After 14 d of treatment,the VAS score in the treatment group was lower than that in the control group,the difference of limb circumference was smaller than that in the control group,and the average blood flow velocity of the vein was faster than that in the control group,the differences were statistically significant(P<0.05).After 14 d of treatment,the staging of lymphedema in the treatment group was better than that before treatment and in the control group,and the differences were statistically significant(P<0.05),there was no significant difference with before treatment in the control group.After 14 d of treatment,the scores of physiological status,social/family status,emotional status and functional status in the treatment group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Air pressure combined with CDT has a significant clinical effect in the treatment of lymphedema after radiotherapy for cervical cancer,it can effectively promote the return of lymph fluid in the retained tissues,reduce the swelling and pain of limbs,and improve the quality of life of patients.
作者
周利平
范美萍
丁玲
王蕾
朱淑芳
张春燕
黄春兰
ZHOU Liping;FAN Meiping;DING Ling;WANG Lei;ZHU Shufang;ZHANG Chunyan;HUANG Chunlan(Department of Radiotherapy,Ganzhou Tumor Hospital,Ganzhou,Jiangxi,341000,China;Department of Obstetrics and Gynecology,The People's Hospital of Ningdu County,Ganzhou,Jiangxi,342800,China)
出处
《当代医学》
2025年第11期95-98,共4页
Contemporary Medicine
基金
江西省赣州市科技计划项目(GZ2021ZSF342)。
关键词
气压
综合淋巴消肿疗法
宫颈癌
放疗
淋巴水肿
生命质量
Air pressure
Complete decongestive therapy
Cervical cancer
Radiotherapy
Lymphedema
Quality of life
