摘要
目的:观察跌打七厘片联合股骨近端抗旋转髓内钉(PFNA)内固定术治疗老年股骨粗隆间骨折患者的效果。方法:回顾性分析2020年10月至2022年10月该院收治的76例老年股骨粗隆间骨折患者的临床资料,根据治疗方法不同将其分为对照组和研究组各38例。对照组给予PFNA内固定术治疗,研究组在对照组基础上联合跌打七厘片治疗。比较两组预后指标(骨痂形成时间、骨折愈合时间、术后负重时间)水平,手术前后骨代谢指标[总Ⅰ型胶原氨基端前肽(TPⅠNP)、β-Ⅰ型胶原C末端肽(β-CTX)、骨钙素(OC)、甲状旁腺激素(iPTH)]水平、髋关节功能(Harris髋关节功能评分标准)评分,以及并发症发生率。结果:研究组骨痂形成时间、骨折愈合时间、术后负重时间均短于对照组,差异有统计学意义(P<0.05);术后3个月,两组TPⅠNP、OC水平均高于术前,且研究组高于对照组,两组β-CTX、i PTH水平均低于术前,且研究组低于对照组,差异有统计学意义(P<0.05);术后1、3个月,两组Harris评分均高于术前,且研究组均高于对照组,差异有统计学意义(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:跌打七厘片联合PFNA内固定术治疗老年股骨粗隆间骨折患者可提高预后,改善骨代谢指标水平,促进髋关节功能恢复,效果优于单纯PFNA内固定术治疗。
Objective:To observe effects of Dieda Qili tablets combined with proximal femoral nail antirotation(PFNA)internal fixation in treatment of elderly patients with intertrochanteric fractures of femur.Methods:A retrospective analysis was conducted on the clinical data of 76 elderly patients with intertrochanteric fractures of femur admitted to this hospital from October 2020 to October 2022.According to different treatment methods,they were divided into control group and study group,38 cases in each group.The control group was treated with PFNA internal fixation,while the study group was treated with Dieda Qili tablets on the basis of that of the control group.The levels of prognostic indexes(callus formation time,fracture healing time,postoperative weight-bearing time),the bone metabolic indexes[total procollagen TypeⅠN-terminal propeptide(TPⅠNP),βC-terminal cross-linked telopeptides of typeⅠcollagen(β-CTX),osteocalcin(OC),and parathyroid hormone(iPTH)]levels and the hip joint function(Harris hip scoring system)score before and after the treatment,and the incidence of complications were compared between the two groups.Results:The callus formation time,the fracture healing time,and the postoperative weight-bearing time in the study group were shorter than those in the control group,and the differences were statistically significant(P<0.05).3 months after the surgery,the levels of TPⅠNP and OC of the two groups were higher than those before the surgery,and those in the study group were higher than those in the control group;the levels ofβ-CTX and iPTH of the two groups were lower than those before the surgery,and those in the study group were lower than those in the control group;and the differences were statistically significant(P<0.05).1 and 3 months after surgery,the Harris scores of the two groups were higher than those before the surgery,those in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusions:Dieda Qili tablets combined with PFNA internal fixation in the treatment of the elderly patients with intertrochanteric fractures of femur can improve the prognosis,enhance the bone metabolic indexes,and promote the recovery of hip joint function.Moreover,it is superior to simple PFNA internal fixation.
作者
董恒利
臧权威
DONG Hengli;ZANG Quanwei(Orthopedics and Traumatology Department of Xiayi County Hospital of Traditional Chinese Medicine,Shangqiu 476400 Henan,China)
出处
《中国民康医学》
2026年第1期110-112,共3页
Medical Journal of Chinese People’s Health
关键词
跌打七厘片
股骨近端抗旋转髓内钉固定术
股骨粗隆间骨折
髋关节功能
骨代谢
预后
并发症
Dieda Qili tablets
Proximal femoral nail antirotation
Intertrochanteric fracture of femur
Hip joint function
Bone metabolism
Prognosis
Complication
