摘要
背景:随着人口老龄化进程的不断加快,老年人肠道微生物的研究受到广泛关注,但如今还缺少对该领域的文献计量学分析。目的:综合分析不同数据库中有关老年人肠道菌群的文献资料,旨在挖掘当前研究热点,并预测未来发展的趋势,为后续研究工作指明可能的发展方向。方法:以“老年人肠道微生物”“老年人肠道微生态”和“老年人肠道菌群”作为主题词字段在中国知网进行检索,以“TS=(elderly gut microbe OR elderly gut microbiome OR elderly gut microbiota OR elderly intestinal microbiome OR elderly intestinal microbiota)”作为检索策略在Web of Science数据库进行检索,使用文献计量工具VOSviewer与CiteSpace,对相关文献的发表年份、国家分布、研究机构、作者和关键词进行系统分析。结果与结论:在中国知网和Web of Science数据库中分别获得有效文献250篇和604篇。在2014-2023年间,全球范围内老年人肠道微生物领域研究发文量整体呈现稳步上升的趋势。国内外对这一领域的关注和探讨热度不断增加,研究深度和广度也在各学科之间的交叉中得到拓展。COVID-19、氧化应激(Oxidative stress)、抑郁(depression)、认知障碍(cognitive impairment)为近2年的突现关键词。通过文献计量学分析,直观展示了老年人肠道微生物领域近10年的研究现状和发展趋势,目前正处于上升期,仍需进一步探索肠道微生物的作用机制及相关疾病的干预方案。
BACKGROUND:As the population ages,research on gut microbiota in the elderly is gaining attention.However,bibliometric analysis in this field is still lacking.OBJECTIVE:To comprehensively analyze literature on gut microbiota in older adults from multiple databases,identify current research hotspots,predict future trends,and provide potential directions for subsequent research.METHODS:CNKI was searched using the subject terms“gut microbiota in older adults,”“gut microecology in older adults,”and“intestinal flora in older adults.”The Web of Science database was searched using the search strategy of“TS=(elderly gut microbe OR elderly gut microbiome OR elderly gut microbiota OR elderly intestinal microbiome OR elderly intestinal microbiota).”Bibliometric tools VOSviewer and CiteSpace were employed to systematically analyze publication years,country distribution,research institutions,authors,and keywords in the retrieved literature.RESULTS AND CONCLUSION:A total of 250 and 604 eligible articles were obtained from the CNKI and Web of Science databases,respectively.From 2014 to 2023,the global publication volume in the field of gut microbiota in older adults showed a steady upward trend.Research interest and discussions in this field have increased significantly worldwide,with expanding depth and breadth through interdisciplinary collaboration.Notably,COVID-19,oxidative stress,depression,and cognitive impairment emerged as prominent keywords in the past 2 years.This bibliometric analysis visually illustrates the research status and developmental trends in the field of gut microbiota in older adults over the past decade.The field is currently in a growth phase,requiring further exploration of underlying mechanisms of gut microbiota and intervention strategies for related diseases.
作者
李一光
郭皓楠
丁晓涛
袁梦瑶
蒋丽晋
范新凤
冯焱
Li Yiguang;Guo Haonan;Ding Xiaotao;Yuan Mengyao;Jiang Lijin;Fan Xinfeng;Feng Yan(Personnel Office,Xinxiang Medical University,Xinxiang 453003,Henan Province,China;School of Public Health,Xinxiang Medical University,Xinxiang 453003,Henan Province,China;College of Life Science,Shanxi Agricultural University,Jinzhong 030801,Shanxi Province,China)
出处
《中国组织工程研究》
北大核心
2026年第23期6071-6080,共10页
Chinese Journal of Tissue Engineering Research
基金
河南省教育教学改革重点课题(2021SJGLX217),项目参与人:李一光。
