摘要
西北燥证是西北地区以燥邪侵袭为主因,以干咳、口鼻咽干、皮肤皲裂、情绪烦躁等津液耗伤为主要症状表现的一组中医证候,是新疆等地居民普遍面临的健康问题和常见的共同病证状态,是冠状动脉粥样硬化性心脏病(简称冠心病)、高血压病等新疆特高发疾病的诱因。在中医藏象理论中,玄府属于微观结构,广泛分布于人体全身,具有畅通气机、输布津液、运行血脉等重要功能。基于“玄府–气液”理论探讨西北燥证病机,认为玄府开阖失司,气液运行失常是关键。水通道蛋白作为运输水分子的跨膜蛋白,广泛存在于中枢系统和外周系统,在维持细胞的水液及离子平衡方面发挥关键作用。本研究基于“玄府–气液”与水通道蛋白在基本属性、功能上的相似之处,探讨西北燥证的病因病机及诊疗原则,深入挖掘“玄府–气液”理论在西北燥证中的应用。
Northwest dryness syndrome is a group of traditional Chinese medicine syndromes characterized by the invasion of dryness pathogen in the northwest region,with dry cough,dry throat and nose,chapping skin,emotional irritability and other symptoms of body fluid consumption as the main manifestations,which is a common health problems and common disease condition faced by the residents in the northwest region,and is the cause of coronary heart disease,hypertension and other diseases with a high incidence in Xinjiang.Xuanfu(sweat pore)is a microscopic structure in the theory of Zangxiang(藏象)in traditional Chinese medicine,which is widely distributed in the human body,and has important functions such as promoting the smooth flow of Qi(气),distributing body fluids,and facilitating blood circulation.Based on the theory of“Xuanfu-Qi and liquid”,the pathogenesis of northwest dryness syndrome is discussed,and it is believed that the key lies in the loss of control over the opening and closing of Xuanfu,which leads to the abnormal circulation of Qi and body liquid.Aquaporins,as transmembrane proteins that transport water molecules,widely exist in the central system and peripheral system,and play a key role in maintaining the water and ion balance inside and outside the cells.In this study,based on the similarities in basic properties and functions between“Xuanfu-Qi and liquid”and aquaporin,the etiology,pathogenesis and diagnosis and treatment principles of northwest dryness syndrome were explored to deeply investigate the application of the theory of“Xuanfu-Qi and liquid”in northwest dryness syndrome.
出处
《中医临床研究》
2025年第27期109-113,共5页
Clinical Journal Of Chinese Medicine
基金
“新疆地区高发疾病研究”教育部重点实验室开放课题(2023A05)
新疆维吾尔自治区中医药青年科技人才专项科研项目(ZYQ2025029)。
关键词
玄府
水通道蛋白
西北燥证
病机
治则
Xuanfu
Aquaporin
Northwest dryness syndrome
Pathogenesis
Treatment principle
