摘要
目的:分析郑州地区过敏性鼻炎(AR)过敏原流行特征。方法:收集2018年9月至2024年1月郑州大学第一附属医院16 161例疑似AR患者的过敏原检测结果,分析过敏原的人群、时间分布特征。结果:16 161例中过敏原特异性IgE(sIgE)阳性12 575例(77.81%),其中10 638例(65.83%)存在多重过敏。过敏原阳性率前3位均为吸入性过敏原,分别为花粉组(44.13%)、动物皮屑组(42.18%)和尘螨组(39.16%)。男性过敏原阳性率大于女性;男性和女性吸入性过敏原阳性率首位均为花粉组,食入性过敏原为海鱼和海蟹。吸入性过敏原青年(>18~40岁)组阳性率最高,未成年(≤18岁)组次之,老年(>65岁)组最低。食入性过敏原老年组阳性率最高,中年(>40~65岁)组次之,未成年组最低。吸入性过敏原秋季阳性率最高(81.40%),夏季次之(75.55%),冬季最低(73.87%)。结论:吸入性过敏原是郑州地区AR的主要过敏原,夏秋季是流行季节,儿童、青少年是主要易感人群。
Aim:To investigate the epidemiological characteristics of allergens of allergic rhinitis(AR)in Zhengzhou.Methods:A total of 16161 patients who were suspected of AR were enrolled from the First Affiliated Hospital of Zhengzhou University between September 2018 and January 2024.The epidemiological characteristics were analyzed using allergen test results.Results:Allergen-specific IgE(sIgE)positive rates was 77.81%(12575/16161),and 10638(65.83%)cases exhibited polysensitisation.All the top three allergens with the highest positive rates were inhalant allergens:pollen(44.13%),animal dander(42.18%),and dust mites(39.16%).The allergen positive rate of the males was higher than that of the females.For both males and females,pollen ranked as the top inhalant allergens,while the most common food allergens were marine fish and crabs.In terms of inhalant allergens,the youth group(>18-40 years)exhibited the highest positive rate,followed by the minor group(≤18 years),and the elderly group(>65 years)showed the lowest.In terms of food allergens,the elderly group had the highest positive rate,with the middle-aged group(>40-65 years)coming next,and the minor group had the lowest rate.Inhalant allergens positive rate was highest in autumn(81.40%),followed by summer(75.55%),while lowest in winter(73.87%).Conclusion:Inhalant allergens are the predominant triggers of AR in Zhengzhou,with a higher prevalence during summer and autumn,and children and adolescents constitute the main susceptible population.
作者
陈卓
董栋
赵玉林
叶琳
CHEN Zhuo;DONG Dong;ZHAO Yulin;YE Lin(Department of Rhinology,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052)
出处
《郑州大学学报(医学版)》
北大核心
2025年第6期830-834,共5页
Journal of Zhengzhou University(Medical Sciences)
基金
河南省中医药科学研究专项课题(2024ZY2139)
河南省国际科技合作项目(242102521064)
河南省医学科技攻关计划联合共建项目(LHGJ20190194)
郑州市科技局基础研究与应用基础研究项目(2024ZZJCYJ055)。
