摘要
目的分析糖尿病足患者足底压力变化与神经传导速度的关系。方法回顾性选取2021年5月—2023年10月乌鲁木齐市第一人民医院分院收治的糖尿病足患者90例的临床资料,根据是否发生神经传导异常将患者分为未发生组(n=48)和发生组(n=42)。比较2组的足底压力参数;采用Pearson相关系数分析足底压力与神经传导速度异常的相关性;多因素Logistic回归分析糖尿病足患者发生神经传导异常的影响因素。结果发生组足底接触面积、最大压力值(PP)、压力—时间累积值(PTI)均高于未发生组(t/P=27.046/<0.001、32.842/<0.001、27.560/<0.001);发生组正中神经、尺神经、桡神经、胫神经、腓神经的传导速度和F波传导速度均低于未发生组(神经传导速度:t/P=9.872/<0.001、8.921/<0.001、9.125/<0.001、10.214/<0.001、8.563/<0.001;F波传导速度:t/P=8.347/<0.001、7.986/<0.001、9.012/<0.001、8.765/<0.001、8.023/<0.001);经Pearson检验发现,足底接触面积、PP、PTI与神经传导速度异常均呈正相关(r/P=0.789/<0.001、0.715/0.002、0.802/<0.001);多因素Logistic回归分析结果显示,足底接触面积大、PP高、PTI高均为糖尿病足患者发生神经传导异常的独立危险因素[OR(95%CI)=2.690(1.864~2.967)、2.401(1.933~3.013)、2.474(1.847~2.842)]。结论足底接触面积、PP、PTI为糖尿病足患者发生神经传导异常的影响因素。
Objective To analyze the relationship between the changes in plantar pressure and nerve conduction velocity in patients with diabetic foot.Methods A total of 90 patients with diabetic foot admitted to our hospital from May 2021 to October 2023 were retrospectively selected as the research subjects.According to whether nerve conduction abnormalities occurred,the patients were divided into the non-occurrence group(n=48)and the occurrence group(n=42).The plantar pressure parameters of the two groups were compared.The Pearson correlation coefficient was used to analyze the correlation between plantar pressure and nerve conduction velocity abnormalities.Multivariate Logistic regression analysis was performed to identify the influencing factors of nerve conduction abnormalities in patients with diabetic foot.Results The plantar contact area,maximum pressure value(PP),and pressure-time integral(PTI)in the occurrence group were all higher than those in the non-occurrence group(t/P=27.046/<0.001,32.842/<0.001,27.560/<0.001).The conduction velocities of the median nerve,ulnar nerve,peroneal nerve,radial nerve,and tibial nerve,as well as the F-wave conduction velocities in the occurrence group were all lower than those in the non-occurrence group(t/P=9.872/<0.001,8.921/<0.001,8.563/<0.001,9.125/<0.001,10.214/<0.001,8.347/<0.001,7.986/<0.001,8.023/<0.001,9.012/<0.001,8.765/<0.001).Pearson's test showed that the plantar contact area,PP,and PTI were all positively correlated with nerve conduction velocity abnormalities(r/P=0.789/<0.001,0.715/0.002,0.802/<0.001).The results of multivariate Logistic regression analysis showed that the increases in plantar contact area,PP,and PTI were all independent risk factors for nerve conduction abnormalities in patients with diabetic foot[OR(95%CI)=2.690(1.864-2.967),2.401(1.933-3.013),2.474(1.847-2.842)].Conclusion The plantar contact area,PP,and PTI are the main factors contributing to nerve conduction abnormalities in patients with diabetic foot.Clinicians should pay attention to patients with diabetic foot whose above indicators are elevated.
作者
裴赵伟
玛依拉·艾则孜
秦国鼎
李米娜
马晨璐
Pei Zhaowei;Mayila Aizezi;Qin Guoding;Li Mina;Ma Chenlu(Department of Internal Medicine,Urumqi First People's Hospital Branch,Xinjiang,Urumqi 830000,China)
出处
《疑难病杂志》
2025年第9期1069-1072,1077,共5页
Chinese Journal of Difficult and Complicated Cases
基金
新疆维吾尔自治区自然科学基金资助项目(2024D01C413)。
关键词
糖尿病足
糖尿病周围神经病变
足底压力
神经传导
相关性
Diabetes foot
Diabetes peripheral neuropathy
Plantar pressure
Nerve conduction
Correlation
