摘要
原发性痛经是指在没有器质性病变的情况下月经期间或月经前后出现的腹部疼痛症状,严重影响女性的生活质量和心理健康。原发性痛经的发生机制复杂,与子宫平滑肌过度收缩、前列腺素过量分泌、炎症反应和神经传导异常等密切相关。针刺在缓解痛经症状、调节全身功能方面疗效显著。通过文献研究发现,针刺可能通过局部穴位效应改善气滞血瘀、寒湿阻滞及肝郁脾虚的病理状态,从而促进气血调和与经络通畅。其作用机制可能与调节前列腺素合成、降低炎症因子释放(如NF-κB相关因子)以及改善神经系统功能等相关,本研究对其进行系统阐述,以期为原发性痛经的治疗研究提供理论依据。
Primary dysmenorrhea refers to abdominal pain occurring during or around menstruation without any identifiable organic pathology,severely affecting women's quality of life and mental health.The pathogenesis of primary dysmenorrhea is complex and closely related to excessive uterine smooth muscle contractions,overproduction of prostaglandins,inflammatory responses,and abnormal neural transmission.Acupuncture has demonstrated significant efficacy in alleviating dysmenorrhea symptoms and regulating overall physiological function.Literature research indicates that acupuncture can act on local acupoints to improve pathological states such as Qi stagnation and blood stasis,cold-damp obstruction,and Liver Qi stagnation with Spleen deficiency,thereby promoting the harmonization of Qi and blood and unblocking meridians.Its therapeutic mechanisms may involve regulating prostaglandin synthesis,reducing the release of inflammatory factors(such as NF-κB-related molecules),and improving nervous system function.This study aims to systematically elaborate on the potential mechanisms in order to provide theoretical support for its treatment and research.
作者
张诗笛
韩昊池
冯博懿
邓海镖
韩亚鹏
韩晗
韩延华
ZHANG Shidi;HAN Haochi;FENG Boyi;DENG Haibiao;HAN Yapeng;HAN Han;HAN Yanhua(Heilongjiang University of Chinese Medicine,Harbin 150040,China;Liaoning University of Traditional Chinese Medicine,Shenyang 110122,China;Shenzhen Guangming District People's Hospital,Shenzhen 518107,China;Tangwei Community Health Service Center,Shenzhen Guangming District People's Hospital,Shenzhen 518107,China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China;The First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)
出处
《针灸临床杂志》
2025年第7期103-108,共6页
Journal of Clinical Acupuncture and Moxibustion
基金
国家中医药管理局“第二批全国中医学术流派传承工作室建设项目”,编号:国中医药人教函[2019]62号。
关键词
原发性痛经
针刺
发病机制
信号通路
Primary dysmenorrhea
Acupuncture
Pathogenesis
Signaling pathway
