摘要
目的:了解洛阳地区育龄女性多囊卵巢综合征(PCOS)发病特点,分析影响发病的相关因素,为制定PCOS防治措施提供参考。方法:选取2021年6月至2024年6月于河南科技大学第一附属医院就诊的724例育龄妇女,以检出的56例PCOS育龄妇女为PCOS组,另选取同期56例体检健康育龄妇女为对照组,采用调查问卷方式收集两组一般临床资料,运用多因素Logistic回归分析影响育龄妇女发生PCOS的高危因素。结果:724例育龄妇女PCOS发病56例,发病率为7.73%;56例PCOS患者年龄主要集中在26~35岁之间,职业以公司职员为主,病程多持续2~5年,临床主要表现为多毛、痤疮、肥胖等高雄激素症状;PCOS组初潮年龄、体质量指数(BMI)、胰岛素抵抗指数(HOMA-IR)、黄体生成素(LH)、雌二醇(E2)水平及近亲PCOS史、父系秃顶、饮食油腻、睡眠质量欠佳、焦虑、抑郁比例高于对照组,规律运动比例低于对照组(P<0.05);多因素Logistic回归分析结果显示,高BMI(OR=2.191,95%CI=1.584~3.224)、高HOMA-IR(OR=3.249,95%CI=2.261~5.946)、饮食油腻(OR=1.957,95%CI=1.218~2.820)、未规律运动(OR=1.807,95%CI=1.196~2.785)、睡眠质量欠佳(OR=2.122,95%CI=1.463~3.096)、焦虑(OR=2.436,95%CI=1.639~3.791)、抑郁(OR=2.770,95%CI=1.727~4.102)是影响育龄妇女发生PCOS的高危因素(P<0.05)。结论:洛阳地区育龄女性PCOS发病与代谢、情绪、运动、饮食习惯有关,需针对高危人群加强健康宣教,以降低PCOS的发生。
Objective:To understand the incidence characteristics of polycystic ovary syndrome(PCOS)among women of childbearing age in Luoyang area,analyze the related factors of the onset the disease,and provide references for formulating prevention and treatment measures for PCOS.Methods:The incidence of PCOS among 724 women of childbearing age who visited the First Affiliated Hospital of Henan University of Science and Technology from June 2021 to June 2024 was collected.Among them,56 women diagnosed with PCOS were included in the PCOS group,and another 56 healthy women of childbearing age undergoing physical examinations during the same period were selected as the control group.General clinical data of the two groups were collected through questionnaires,and multivariate logistic regression analysis was used to identify the high-risk factors influencing the occurrence of PCOS among women of childbearing age.Results:Among the 724 women of childbearing age,56 cases of PCOS were identified,with an incidence rate of 7.73%.The 56 PCOS patients were mainly aged between 26 and 35 years old,mostly worked as company employees,and had a disease duration mostly lasting 2 to 5 years.The main clinical manifestations were hyperandrogenic symptoms such as hirsutism,acne and obesity.The PCOS group had higher ages at menarche,body mass index(BMI),homeostasis model assessment of insulin resistance(HOMA-IR),luteinizing hormone(LH),estradiol(E2)levels,as well as a higher proportion of family history of PCOS,paternal baldness,greasy diet,poor sleep quality,anxiety and depression compared to the control group,while the proportion of regular exercise was lower(P<0.05).Multivariate logistic regression analysis results showed that high BMI(OR=2.191,95%CI=1.584~3.224),high HOMA-IR(OR=3.249,95%CI=2.261~5.946),greasy diet(OR=1.957,95%CI=1.218~2.820),lack of regular exercise(OR=1.807,95%CI=1.196~2.785),poor sleep quality(OR=2.122,95%CI=1.463~3.096),anxiety(OR=2.436,95%CI=1.639~3.791)and depression(OR=2.770,95%CI=1.727~4.102)were high-risk factors influencing the occurrence of PCOS among women of childbearing age(P<0.05).Conclusion:The incidence of PCOS among women of childbearing age in Luoyang area is related to metabolism,emotions,exercise and dietary habits.It is necessary to strengthen health education for high-risk populations to reduce the occurrence of PCOS.
作者
马晓鑫
王莹
赵雪
MA Xiaoxin;WANG Ying;ZHAO Xue(Department of Gynecology,The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,China)
出处
《黑龙江医药科学》
2025年第9期33-36,共4页
Heilongjiang Medicine and Pharmacy
基金
2022年度河南省医学科技攻关联合共建项目,编号:LHGJ20221071。
关键词
育龄妇女
多囊卵巢综合征
发病风险
防治措施
women of childbearing age
polycystic ovary syndrome
incidence risk
prevention and treatment measures
