摘要
目的建立消炎木尼孜其颗粒的质量标准。方法采用薄层色谱法对制剂中菟丝子、香青兰进行定性鉴别;采用高效液相色谱法同时测定制剂中金丝桃苷和田蓟苷的含量。结果消炎木尼孜其颗粒中菟丝子、香青兰定性鉴别结果清晰。金丝桃苷、田蓟苷的质量浓度分别在11.9322~95.4576μg·mL^(-1)(r=0.9999)和25.28178~202.25424μg·mL^(-1)(r=0.9994)范围内线性关系良好,平均加样回收率分别为99.11%、99.52%,相对标准偏差(RSD)分别为0.47%、0.72%(n=6)。结论建立的质量控制方法简单可靠、专属性强,可用于消炎木尼孜其颗粒的质量控制。
Objective Establishment of quality standards for Xiaoyan Muniziqi granules(XYMNZQG).Methods The qualitative identification of Cuscutae Semen and Dracocephalum moldavia in the preparation was carried out,and the content of hyperin and tilianin in the preparation was determined.Results The qualitative results of Cuscutae Semen and Dracocephalum moldavia in XYMNZQG were clear.The linear ranges of hyperin and tilianin were 11.9322-95.4576μg·mL^(-1)(r=0.9999)and 25.28178-202.25424μg·mL^(-1)(r=0.9994),respectively.The average recoveries were 99.11%and 99.52%,with RSDs of 0.47%and 0.72%(n=6).Conclusion The established quality control method is simple,reliable,and specific,and can be used for the quality control of XYMNZQG.
作者
赵婷婷
郭君婷
叶斯木·塔拉甫别克
阿布都西库尔·托合提
刘桂花
ZHAO Tingting;GUO Junting;YESEM Talpbek;ABUDUXIKUER Tuoheti;LIU Guihua(Key Laboratory of Xinijang Uygur Medicine,Xinjiang Institute of Materia Medica,Urumqi 830000,China;Zepu Uygur Medical Hospital,Kashgar 844800,China)
出处
《医药导报》
北大核心
2025年第9期1477-1481,共5页
Herald of Medicine
基金
新疆维吾尔自治区重点实验室项目(2023D04035)
2023年中央财政转移支付地方项目
新疆维吾尔自治区重大科技专项项目(2022A03017-1)。
关键词
消炎木尼孜其颗粒
质量标准
薄层色谱法
高效液相色谱法
Xiaoyan Muniziqi granules
Quality standard
Thin-layer chromatography
High performance liquid chromatography
