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非酒精性脂肪性肝炎研究进展

Research progress of nonalcoholic steatohepatitis
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摘要 非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)作为最常见的慢性肝病之一,全球患病率约为25%,是肝移植手术的适应证之一。非酒精性脂肪性肝炎(non-alcoholic steatohepatitis,NASH)是NAFLD的炎症亚型,其与疾病进展和全因病死率升高相关。区分NAFLD、NASH以及NASH的分期是重要的临床问题。本文综述了目前研究关于NASH的发病机制、生物标志物及影像技术,用以评估肝脂肪变性和纤维化的严重程度,以期为NASH的非侵入性诊断和准确风险分层提供依据。
作者 冯厚涵 靳士豪 刘鑫 孙雁 方明星 Feng Houhan;Jin Shihao;Liu Xin;Sun Yan;Fang Mingxing
机构地区 河北医科大学基础医学院 天津市第一中心医院外科重症医学科 河北医科大学第三医院重症医学科
出处 《实用器官移植电子杂志》 2025年第4期371-374,共4页 Practical Journal of Organ Transplantation(Electronic Version)
基金 河北省中医药管理局科研计划项目(T2025013) 感染性疾病国家临床重点专科建设项目经费资助(8235)。
关键词 非酒精性脂肪性肝炎 发病机制 生物标志物 影像学诊断 肝移植
分类号 R575.5 [医药卫生—消化系统]
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实用器官移植电子杂志
2025年 第4期

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