摘要
目的 探讨急性感染后非特异性炎症因子降钙素原(PCT)、纤维蛋白原(Fbg)、D-二聚体(D-D)与急性心肌梗死(AMI)冠脉严重程度的相关性及临床意义。方法 分析2023年1月—2024年3月本院心内科收治的经选择性冠状动脉造影证实的AMI患者共85例。其中,有明确感染证据的45例,将其设为感染AMI组。无感染证据的40例,将其设为非感染AMI组。记录患者的一般资料、实验室结果、冠脉造影情况,根据患者冠脉造影的冠脉严重程度,按照相关评分标准计算Gensini积分。比较两组间临床指标及Gensini积分,分析PCT、Fbg、D-D水平与冠脉严重程度的关系。结果 感染AMI组冠脉严重程度明显高于非感染AMI组(P<0.01),差异有统计学意义;感染AMI组轻度、中度、重度患者PCT、Fbg、D-D水平均明显高于非感染AMI组,差异有统计学意义(P<0.05)。结论 急性感染非特异性炎症因子(PCT、Fbg、D-D)水平与冠脉病变严重程度相关,表明急性感染是心血管事件的危险因素,可为后续临床诊治提供依据。
Objective To explore the correlation and correlation of the correlation and the correlation of non-specific inflammatory inflammatory factor calculin(PCT),fibrin(FBG),D-D-D(D-D),and acute myocardial infarction(AMI)Clinical significance.Methods Analyze from January 2023 to March 2024,a total of 85 AMI patients confirmed by the Selective Coronary Alarms of Our Internal Medicine of Our hospital,including 45 cases of clear evidence of infection,and the infection AMI group was the observation group.40 cases without infection,set up a non-infected AMI group as the control group.Record the general data,laboratory results,and coronary angiography of the patient,and calculate the Gensini points according to the severity of the coronary angiography of the patient's coronary pulse.Compare the differences in clinical indicators and Gensini points between the two groups;analyze the relationship between PCT,FBG,D-D level and the severity of coronary veins.Results The severity of the coronary veins infected in the AMI group was significantly higher than that of non-infected AMI groups,and the differences were significant(both P<0.01);The average levels of PCT,Fbg,and D-D in patients with mild,moderate,and severe AMI infection were higher than those in the non infected AMI group,and the difference was statistically significant(P<0.05).Conclusion Data show that the level of acute infection non-specific inflammatory factor(FBG,D-D)is related to the severity of coronary path lesions,indicating that acute infection is a risk factor for cardiovascular events,which can provide a basis for subsequent clinical diagnosis and treatment.
作者
南宇静
刘颖
杨彤
NAN Yujing;LIU Ying;YANG Tong(Changchun University of Traditional Chinese Medicine,Jilin Changchun 130117;Jilin FAW General Hospital,Jilin Changchun 130011)
出处
《智慧健康》
2025年第14期40-43,共4页
Smart Healthcare
关键词
急性感染
非特异性炎症因子
急性心肌梗死
冠脉严重程度
Acute infection
Non-specific inflammatory factor
Acute myocardial infarction
Severity of coronary veins
