摘要
目的探讨脂蛋白相关磷脂酶A2(Lp-PLA2)、B型钠尿肽(BNP)的检测在冠心病预后预测中的意义。方法收集冠脉造影确诊的48例冠心病患者进行研究:①不同冠脉病变程度的Lp-PLA2和BNP水平;②通过随访,研究不同Lp-PLA2和BNP水平下冠心病患者的心血管事件发生率。结果①非严重病变组的Lp-PLA2水平(P<0.01)和BNP水平(P<0.05)均低于严重病变组。②高Lp-PLA2组和高BNP组的心血管事件的发生率均高于低Lp-PLA2组(P<0.05)和低BNP组(P<0.01)。结论血浆BNP和Lp-PLA2水平可预测冠心病的严重程度和预后,应对高BNP和Lp-PLA2水平的患者进行有效的预防。
Objective To explore the prognostic significance of lipoprotein - associated phospholipase A2 and B - type na- triuretie peptide testing in the coronary heart disease. Methods Totally 48 patients with coronary heart disease diagnosed by coronary angiography were collected in the study. ①Lp - PLA2 and BNP level of different degrees of coronary artery disease ;②To study the incidence of cardiovascular events of patients with CHD under different Lp - PLA2 and BNP levels through follow - up. Results （~）The Lp - PLA2 level （ P 〈 0. 01 ） and BNP level （P 〈 0. 05 ） of non - advanced lesions group were lower than that in advanced lesions groups ;③The incidence of cardiovascular events in high Lp - PLA2 group and high BNP group were higher than that of the low Lp - PLA2 group and low BNP group. Conclusions Plasma BNP and Lp - PLA2 levels can predict the severity and prognosis of coronary heart disease, which is worth being promoted.
出处
《医药论坛杂志》
2012年第3期28-29,共2页
Journal of Medical Forum
关键词
脂蛋白相关磷脂酶A2
B型钠尿肽
冠心病
预后预测
Lipoprotein - associated phospholipase A2
B - type natriuretic peptide
Coronary heart disease
Prognosis
