摘要
目的:探究采用经阴道三维超声评估子宫内膜容受性(ER)在排卵障碍性不孕患者治疗后妊娠中的预测价值。方法:纳入2022年1月—2025年1月于江西中医药大学附属医院接受诊疗的80例排卵障碍性不孕患者。所有患者均接受相同的促排卵治疗,在人绒毛膜促性腺激素(human chorionic gonadotrophin,hCG)治疗当天检测血清性激素[孕酮(P)、雌二醇(E_(2))]水平,并进行经阴道三维超声检查,获得ER相关参数指标[子宫内膜容积(EMV)、子宫内膜厚度(EMT)及子宫内膜下血管指数(VI)、血流指数(FI)、血管化血流指数(VFI)]水平。根据患者治疗后的妊娠情况进行分组,治疗后妊娠患者纳入孕育组(n=53),未妊娠患者纳入不孕组(n=27),对两组上述血清性激素及ER相关参数指标水平进行比较,并绘制ROC曲线分析经ER预测排卵障碍性不孕患者治疗后妊娠的价值。结果:两组hCG治疗当天血清P、E_(2)及EMT、子宫内膜下FI水平比较,差异无统计学意义(P>0.05);不孕组hCG治疗当天EMV及子宫内膜下VI、VFI水平低于孕育组(P<0.05)。ROC曲线分析结果显示,EMV及子宫内膜下VI、VFI水平预测排卵障碍性不孕患者治疗后妊娠的AUC值分别为0.856、0.769、0.885,敏感度分别为92.59%、51.85%、100%,特异度分别为71.70%、88.68%、66.04%。结论:经阴道三维超声中对EMV及子宫内膜下VI、VFI水平进行检测,可以预测排卵障碍性不孕患者治疗后妊娠情况。
Objective:To explore the predictive value of transvaginal three-dimensional ultrasound in evaluating endometrial receptivity(ER)for pregnancy in patients with ovulation disorder infertility after treatment.Method:A total of 80 patients with ovulatory disorder infertility who received diagnosis and treatment in the Affiliated Hospital of Jiangxi University of TCM from January 2022 to January 2025 were included.All patients received the same ovulation induction treatment.On the day of human chorionic gonadotrophin(hCG)treatment,the levels of serum sex hormones[progesterone(P),estradiol(E_(2))]were detected,and transvaginal three-dimensional ultrasound was performed to obtain ER-related parameters[endometrial volume(EMV),endometrial thickness(EMT),subendometrial vascularity index(VI),flow index(FI)and vascularization flow index(VFI)].The patients were grouped according to their pregnancy conditions after treatment,the pregnant patients after treatment were included in the pregnant group(n=53)and the non-pregnant patients were included in the infertility group(n=27).The levels of the above-mentioned serum sex hormones and ER-related parameter indicators in the two groups were compared,and the ROC curve was drawn to analyze the value of ER in predicting pregnancy in patients with ovulation disorder infertility after treatment.Result:There were no statistically significant differences in the levels of serum P,E_(2),EMT and subendometrial FI between the two groups on the day of hCG treatment(P>0.05).On the day of hCG treatment,the levels of EMV,subendometrial VI and VFI in the infertility group were lower than those in the pregnancy group(P<0.05).The results of ROC curve analysis showed that the AUC value of EMV and subendometrial VI and VFI levels in predicting pregnancy in patients with ovulation disorder infertility after treatment were 0.856,0.769,and 0.885,respectively,and the sensitivities were 92.59%,51.85%,and 100%,respectively,the specificities were 71.70%,88.68% and 66.04%,respectively.Conclusion:The detection of EMV,subendometrial VI and VFI levels in transvaginal three-dimensional ultrasound can predict the pregnancy status of patients with ovulation disorder infertility after treatment.
作者
万娟
刘招友
WAN Juan;LIU Zhaoyou(Department of Ultrasound,the Affiliated Hospital of Jiangxi University of TCM,Nanchang 330006,China;不详)
出处
《中国医学创新》
2025年第22期107-110,共4页
Medical Innovation of China
关键词
经阴道三维超声
排卵障碍性不孕
子宫内膜容受性
预测价值
妊娠
Transvaginal three-dimensional ultrasound
Ovulation disorder infertility
Endometrial receptivity
Predictive value
Pregnancy
