摘要
目的 观察针刺配合人绒毛膜促性腺激素(HCG)治疗未破裂卵泡黄素化综合征(LUFS)性不孕症疗效。方法 将我院92例LUFS患者随机分为对照组与观察组各46例。对照组采用HCG治疗,观察组采用针刺配合HCG。比较两组临床疗效,妊娠率和排卵率,宫颈黏液评分、子宫内膜厚度,卵巢动脉最大血流速度(PSV)、阻力指数(RI)、搏动指数(PI)、黄体生成素(LH)和雌二醇(E_(2))。结果 治疗后,观察组总有效率高于对照组(P<0.05);观察组妊娠率和排卵率均高于对照组(P<0.05);两组宫颈黏液评分、子宫内膜厚度、卵巢动脉PSV均高于治疗前,PI、RI均低于治疗前,观察组宫颈黏液评分、卵巢动脉PSV、子宫内膜厚度均高于对照组,PI、RI均低于对照组(P<0.05);两组LH、E_(2)均高于治疗前,观察组LH、E_(2)均高于对照组(P<0.05)。结论 针刺配合HCG治疗LUFS协同作用显著,提高妊娠率和排卵率,疗效肯定,改善宫颈黏液和子宫内膜容受性,调节性激素水平。
Objective To observe the efficacy of acupuncture combined with human chorionic gonadotropin(HCG)in treatment of infertility with luteinized unruptured follicle syndrome(LUFS).Methods A total of 92 patients with LUFS were randomly divided into control group and observation group,with 46 cases in each group.Control group was treated with HCG,while observation group was treated with acupuncture and HCG.The efficacy,pregnancy rate and ovulation rate,cervical mucus score,endometrial thickness,ovarian arterial Peak Systolic fiow Velocity(PSV),resistance index(RI),pulse index(PI),luteinizing hormone(LH),and estrogen(E_(2))were compared between the two groups.Results After treatment,the total effective rate of the observation group was higher than that of control group(P<0.05);the pregnancy rate and ovulation rate in observation group were higher than those in control group(P<0.05);the cervical mucus score,endometrial thickness,and ovarian artery PSV of both groups were higher than those before treatment,while the PI and RI were lower,and the above indicators were superior in treatment group to those in control group(P<0.05);the LH and E_(2) in both groups were higher than those before treatment,which were higher in observation group than control group(P<0.05).Conclusion Acupuncture combined with HCG has a significant synergistic effect in treatment of LUFS,which can improve pregnancy rate and ovulation rate,improve cervical performance and endometrial conditions,and regulate sex hormone levels.
作者
冯艳霞
刘筱茂
李宝宝
李春春
窦娜
FENG Yan-xia;LIU Xiao-mao;LI Bao-bao;LI Chun-chun;DOU Na(The Third Department of Gynaecology,Yulin Hospital of TCM,Yulin 719000)
出处
《湖北中医药大学学报》
2025年第1期95-97,共3页
Journal of Hubei University of Chinese Medicine
基金
陕西省中医药管理局重点研究室项目(陕中医药发[2024]5号)。
关键词
未破裂卵泡黄素化综合征
不孕症
针刺
人绒毛膜促性腺激素
Unruptured follicle luteinization syndrome
Infertility
Acupuncture
Human chorionic gonadotropin
