摘要
针对器官芯片研究所需要的弹性阵列微孔薄膜,研究制作高密度阵列微米孔径的基于聚二甲基硅氧烷(PDMS)薄膜的方法,包括硅基模板表面性质的影响,PDMS薄膜浇筑和固化成型的条件及薄膜从硅基模板的剥离情况等。根据目视观察和激光扫描仪检测结果,表面镀有SiO2的硅基模板经过氟硅烷处理,在精确控制浇筑量和固化温度的基础上,进一步进行重力辅助保压固化,并通过覆盖在PDMS上一起固化的PC薄膜可将阵列微孔PDMS薄膜从硅模板上完整剥离下来。
Aiming at the elastic array microporous films needed for organ chip research,methods for making polydimethylsiloxane(PDMS)-based films with high density array micro-apertures were studied,including the influence of surface properties of silicon-based templates,pouring and curing of the PDMS films.Conditions and peeling of the films from the silicon-based templates.According to visual observation and laser scanner detection results,the silicon-based template coated with SiO2 on the surface was treated with fluorosilane.Based on accurately controlling the pouring amount and curing temperature,it was further subjected to gravity-assisted pressure-retaining curing,and covered with PDMS The PC film cured together on the PDMS completely peeled off the array microporous PDMS film from the silicon template.
出处
《科技创新与应用》
2025年第21期56-59,共4页
Technology Innovation and Application
关键词
聚二甲基硅氧烷
多孔薄膜
硅片
硅烷化
实验设备
polydimethylsiloxane
porous membrane
silicon wafer
silanization
experimental equipment
