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基于数据挖掘分析中医药治疗梅核气用药规律

Analysis on Medication Rules of Chinese Medicine for Globus Hystericus Based on Data Mining
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摘要 目的:基于数据挖掘探讨中医药治疗梅核气的用药规律。方法:检索中国知网(CNKI)数据库关于中医药治疗梅核气的文献,时限为2000—2023年,运用Microsoft Office Excel 2010软件统计中药使用频数、性味、归经及功效,IBM SPSS Statistics 25.0软件进行聚类分析、IBM SPSS Modeler18.0软件进行关联规则分析。结果:共有62篇文献符合纳入标准,共涉及155味中药,用药频数≥6的共有45味中药,排前4位的中药有半夏、茯苓、厚朴、甘草。药性以温性、平性为主。药味以甘、辛、苦为主。归经以肺、脾、肝经为主。功效以理气药、化痰止咳平喘药、清热药、补虚药为主。药物关联分析中二项药物关联半夏-茯苓支持度最高,三项药物关联厚朴-茯苓-半夏支持度最高。高频中药(频数≥15)进行聚类,归为4类。结论:梅核气以气和痰为主要病因,用药以理气药和化痰止咳平喘药为主,临床上可着重考虑厚朴-茯苓-半夏配伍应用。 Objective:To discuss the medication rules of Chinese medicine for globus hystericus based on data mining.Methods:The literature from 2000 to 2023 on the treatment of globus hystericus by Chinese medicine in database of China National Knowledge Infrastructure(CNKI)was searched.Microsoft Office Excel 2010 software was used for the statistics of the frequency,nature and flavor,meridian entries and effects of Chinese medicinals.IBM SPSS Statistics 25.0 software was used for the cluster analysis,and IBM SPSS Modeler 18.0 software for the association rule analysis.Results:A total of 62 articles met the inclusion criteria,involving 155 Chinese medicinals.Among them,45 Chinese medicinals were used for more than six times,and the top four are Pinelliae Rhizoma,Poria,Magnoliae Officinalis Cortex and Glycyrrhizae Radix et Rhizoma.The Chinese medicinals are mainly warm and neutral in nature,and mainly sweet,acrid and bitter in flavor with the main meridian entries of the lung,spleen and liver.They are mainly used for regulating qi,dissolving phlegm,easing cough and relieving panting,clearing heat,and tonifying deficiency.According to the association rule analysis,the pairwise association between Pinelliae Rhizoma and Poria demonstrated the highest support,and the triple association among Magnoliae Officinalis Cortex,Poria and Pinelliae Rhizoma had the highest support.Highly used(≥15 times)Chinese medicinals were clustered into four categories.Conclusion:Globus hystericus is mainly caused by qi disfunction and phlegm retention,and the Chinese medicinals for qi-regulating and phlegm-dissolving,cough-easing and panting-relieving are the main medications.In clinical practice,the compatibility of Magnoliae Officinalis Cortex-Poria-Pinelliae Rhizoma can be considered.
作者 刘玉 赵星 LIU Yu;ZHAO Xing(Longxian People's Hospital,Longxian Shaanxi 721200,China)
机构地区 陇县人民医院
出处 《新中医》 2025年第13期6-10,共5页 New Chinese Medicine
关键词 梅核气 数据挖掘 用药规律 关联规则 聚类分析 Globus hystericus Data mining Medication rules Association rules Cluster analysis
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