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温针灸联合他达拉非治疗中老年勃起功能障碍的临床疗效及安全性研究

Efficacy of Warm Acupuncture Combined with Tadalafil in the Treatment of Erectile Dysfunction of Middle-Aged and Elderly Patients
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摘要 【目的】探讨温针灸联合他达拉非治疗中老年勃起功能障碍(ED)的临床疗效及安全性。【方法】选择2022年6月至2024年5月本院收治的98例中老年ED患者,根据随机数字表法分为对照组和观察组,每组49例。对照组给予常规他达拉非治疗,观察组在对照组的基础上联合温针灸治疗,总疗程为6周。比较两组的临床疗效、国际勃起功能指数(IEF-5)评分、阴茎硬度评分(EHS)、性满意度量表(SS)评分及血清总睾酮水平,并记录慢肌(Ⅰ类)测试值、快肌(Ⅱ类)测试值、耐力测试值及治疗过程中不良事件的发生情况。【结果】观察组的总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,两组IEF-5评分、EHS、SS评分及血清总睾酮水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);两组患者慢肌(Ⅰ类)测试值、快肌(Ⅱ类)测试值和耐力测试值均高于治疗前,观察组均高于对照组,差异有统计学意义(P<0.05)。两组患者治疗期间均未发生严重不良反应。【结论】温针灸联合他达拉非治疗中老年勃起功能障碍具有较好的临床疗效,能够显著改善勃起功能,提高性满意度,且未增加不良事件的发生率。 【Objective】To investigate the efficacy of warm acupuncture combined with tadalafil in the treatment of erectile dysfunction(ED)of middle-aged and elderly patients.【Methods】A total of 98 middle-aged and elderly ED patients admitted to Tianshui Hospital of Integrated Traditional Chinese and Western Medicine from June 2022 to May 2024 were randomly divided into two groups,with 49 cases in each group.The control group received conventional tadalafil treatment,while the observation group was additionally treated with warm acupuncture.The total treatment duration was 6 weeks.Clinical efficacy was compared between the two groups by evaluating the International Index of Erectile Function(IEF-5),Erection Hardness Score(EHS),total serum testosterone(tT)levels,Sexual Satisfaction Scale(SS),The measurement of slow-twitch muscle(TypeⅠ)and fast-twitch muscle(TypeⅡ),and the endurance test values.Adverse events during treatment were also recorded.【Results】The total effective rate in the observation group was higher than that in the control group(P<0.05).After treatment,the IEF-5 scores,EHS,SS scores and serum total testosterone levels of the two groups were higher than those before treatment.After 6 weeks of treatment,the levels of IEF-5,EHS,SS scores,and serum tT in the observation group were higher than those in the control group(P<0.05).The measurement of slow-twitch muscle(TypeⅠ)and fast-twitch muscle(TypeⅡ),as well as their endurance test values of the two groups of patients were higher than those before treatment.And these test values in the observation group were also higher than those in the control group(P<0.05).【Conclusion】Warm acupuncture combined with tadalafil has a significant clinical efficacy in treating erectile dysfunction in middle-aged and elderly patients,significantly improving erectile function and sexual satisfaction without increasing the incidence of adverse events.
作者 陈利军 赵治坚 夏浩 CHEN Lijun;ZHAO Zhijian;XIA Hao(Department of Urology,Tianshui Integrated Traditional Chinese and Western Medicine Hospital,Tianshui Gansu 741020)
出处 《医学临床研究》 2025年第6期1030-1032,1036,共4页 Journal of Clinical Research
关键词 勃起功能障碍 温针疗法 他达拉非 治疗结果 Erectile Dysfunction Needle Warming Therapy Tadalafil Treatment Outcome
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